Publications by authors named "Kara Short"

Introduction: Neonatal renal replacement therapy (RRT) is a treatment modality used for severe kidney failure. Historically, its use has been limited in small infants due to circuits with large extra-corporeal volumes that require large double lumen vascular catheters. We sought to review our institution's experience with vascular access and overall survival in infants who receive RRT.

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Background: Prophylactic peritoneal dialysis (PD) in neonates undergoing cardiopulmonary bypass (CPB) is safe and improves outcomes. We sought to (1) derive the pre-operative characteristics of neonates who are most likely to benefit from PD after CPB and (2) validate a new prophylactic PD protocol based on our retrospective analysis.

Methods: First, we retrospectively evaluated neonates requiring cardiac surgery with CPB from October 2012 to June 2016.

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Article Synopsis
  • * A study involving 31 neonates with congenital kidney failure at Children's of Alabama found that 5 required ECMO due to severe respiratory distress; diagnoses included kidney abnormalities like posterior urethral valves and renal dysplasia.
  • * Among the 5 patients on ECMO, 4 survived with improved pulmonary conditions, 3 received kidney transplants, and findings suggest that thorough supportive care can lead to better long-term outcomes, challenging the notion of nonviability.
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Introduction: Shiga-toxin associated-hemolytic uremic syndrome (STEC-HUS) is a severe cause of acute kidney injury (AKI) in children. Although most children recover, about 5% die and 30% develop chronic renal morbidity. HUS pathophysiology includes activated neutrophils damaging vascular endothelial cells.

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