Publications by authors named "Kara Magee"
Article Synopsis
- - The study aimed to discover how common undiagnosed malignant tumors are in healthy middle-aged to older dogs, specifically those aged 5.5 to 11.5 years.
- - Out of 902 screened dogs, 2.7% were diagnosed with cancer, while an additional 3.3% had abnormalities that could indicate malignancy, raising the total to 6.0% when including suspected cases.
- - The findings highlight that thorough physical exams, especially with aspiration cytology, are essential for effectively screening for cancer in older dogs.
Rationale: Murine syngeneic tumor models have revealed efficacious systemic antitumor responses following primary tumor in situ vaccination combined with targeted radionuclide therapy to secondary or metastatic tumors. Here we present studies on the safety and feasibility of this approach in a relevant translational companion dog model (n = 17 dogs) with advanced cancer.
Methods: The three component of the combination immuno-radiotherapy approach were employed either separately or in combination in companion dogs with advanced stage cancer.