Publications by authors named "Kara Kolar"

Myotonic Dystrophy Type 2 (DM2) is a genetic disease caused by expanded CCTG DNA repeats in the first intron of . The number of CCTG repeats in DM2 patients ranges from 75-11,000, yet little is known about the molecular mechanisms responsible for repeat expansions or contractions. We developed an experimental system in that enables selection of large-scale contractions of (CCTG) within the intron of a reporter gene and subsequent genetic analysis.

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