Evaluation of vitamin D repletion regimens to correct vitamin D status in adults.

Objective: To determine the efficacy and safety of commonly prescribed regimens for the treatment of vitamin D insufficiency.

Methods: We performed a retrospective analysis of 306 consecutive patients who were prescribed ergocalciferol (vitamin D2) for correction of vitamin D insufficiency at the Atlanta Veterans Affairs Medical Center between February 2003 and May 2006. Serum levels of parathyroid hormone, 25-hydroxyvitamin D (25-OHD), and calcium were compared before and after treatment with ergocalciferol.