Anti-M Alloimmunization: Management and Outcome at a Single Institution.

 The objective of this study was to review the management strategies and outcomes in gravidas with anti-M alloimmunization over 15 years.  Data collected from 195 pregnant patients with anti-M antibodies from July 2000 through June 2016 were reviewed retrospectively. We analyzed indirect antiglobulin test titer results, paternal or fetal/neonatal M antigen status, antepartum course, and perinatal outcomes.

Hemolytic disease of the fetus and newborn due to multiple maternal antibodies.

Objective: The objective of the study was to determine whether women with combinations of red blood cell antibodies are more likely to develop significant hemolytic disease of the fetus and newborn than those with single antibodies.

Study Design: A retrospective exposure cohort study was conducted of pregnant women with red blood cell antibodies. The development of significant hemolytic disease of the fetus and newborn was then compared between patients with single antibodies and those with multiple antibodies.