Cytokine release by human bone marrow stromal cells isolated from osteoarthritic and diabetic osteoarthritic patients .

Objectives: Primary Osteoarthritis (OA) is a disease of progressive joints degeneration due to idiopathic causes. Recent evidence showed a positive relationship between OA and metabolic syndrome. This pilot study aimed to assess the baseline level of pro and anti-inflammatory cytokines in OA patients with or without Diabetic Mellitus (DM) and assess the effect of hydrogen peroxide (HO) in cytokine production.