MicroRNAs and other biomarkers of atrial fibrillation in ischemic stroke patients.

This study aimed to evaluate the ability of selected microRNAs as biomarkers of atrial fibrillation (AF) in ischemic stroke patients in comparison with other established biochemical biomarkers. A prospective case-control study of consecutive ischemic stroke patients with AF admitted to a comprehensive stroke center was conducted. The control group consisted of patients with ischemic stroke with no AF detected on prolonged (at least 3 weeks) Holter ECG monitoring.

Effect of a Single Dose of Deflazacort on Postoperative Pain, Swelling, and Trismus after Impacted Lower Third Molar Surgery: Randomised Clinical Trial.

: The aim of this study was to investigate the efficacy of a single preoperative dose of deflazacort on pain, swelling, and trismus after impacted lower third molar surgery. : This randomised, prospective, double-blind, split-mouth clinical study included 26 healthy individuals with bilaterally impacted lower third molars. Group 1 was given a placebo (single-dose vitamin C tablet), and group 2 was given a single 30 mg dose of deflazacort 1 h prior to surgery.

The impact of earthquakes on women: assessing women's mental health in aftermath of the Kahramanmaraş-centred earthquake in Türkiye.

Background: Earthquakes disproportionately affect women and exacerbate gender and social inequalities. This study aims to investigate the psychological impact of the earthquake in Türkiye on women and the associated factors.

Methods: This is a survey-based study.

A Troublesome Complication of Hydatid Cysts; Intra-Abdominal Rupture: A 10-Year Study from a High-Volume Center.

Background: Hydatid cyst is a parasitic infection, often caused by . Although it is classified as a benign disease, cyst ruptures in the abdomen can be fatal. Ruptures occur spontaneously or after trauma.

The association between posttraumatic stress disorder and mental health of adolescents who exposed to the worst disaster of the century: Extensive data from southeast Turkey.

Problems: This study was conducted to examine the association between posttraumatic stress disorder and mental health status of adolescents exposed to the worst disaster of the century.

Methods: This study was descriptive, cross-sectional, and correlational. This research was conducted between March 31 and July 1, 2023.

Tissue factor-heparanase complex: intracellular nonhemostatic effects.

Background: Heparanase, known to be involved in angiogenesis, cancer progression, and inflammation, was shown to form a complex with tissue factor (TF) via its procoagulant domain and to enhance the hemostatic system.

Objectives: To reveal a potential role of heparanase procoagulant domain in nonhemostatic effects.

Methods: Effects of peptides 16 and 16AC derived from the heparanase procoagulant domain, discovered by our group, were studied using the XTT proliferation assay, western blot analysis, and immunostaining and a mouse wound-healing model.

Evaluation of the efficacy of topical rifamycin application on postoperative complications after lower impacted wisdom teeth surgery.

Purpose: This study aimed to evaluate the efficacy of a single-dose topical rifamycin application on postoperative complications after impacted lower third molar surgery.

Materials And Methods: This prospective, controlled clinical study consisted of individuals with bilaterally impacted lower third molars that would be extracted for orthodontic reasons. The extraction sockets were irrigated with 3 ml/250 mg of rifamycin solution in Group 1, while in Group 2 (control group) the extraction sockets were irrigated with 20 ml of physiological saline.

Effect of combined boric acid and chlorhexidine mouthwashes on postoperative complications and periodontal healing after impacted third molar surgery: a-double blind randomized study.

Objectives: This study aimed to evaluate the effects of different concentrations of boric acid (BA) combined with chlorhexidine (CHX) mouthwash on postoperative complications and periodontal healing following impacted third molar surgery.

Materials And Methods: A total of 80 patients were randomly divided into eight groups. The patients in the study groups received different concentrations of BA ranging from 0.

The relationship between frontal sinus dimensions and skeletal malocclusion.

Purpose: The aim of this retrospective research is to compare frontal sinus dimensions in skeletal Class I, skeletal Class II, and skeletal Class III individuals and to evaluate the relationship of these dimensions with anterior skull base length and some cephalometric values.

Materials And Methods: In this research, we used lateral cephalometric radiographs of 60 people aged 17 to 25. In individuals with skeletal Class I malocclusion, skeletal Class II malocclusion due to mandibular insufficiency, and skeletal Class III malocclusion due to mandibular excess, measurements of frontal sinus length and height as well as S-N, Co-A and Co- Gn lengths, ANB0, FMA0, SN-GoGn0 angles values were performed.

Mental Health States of Housewives: an Evaluation in Terms of Self-perception and Codependency.

Housewives are individuals who assume the role of caregiver in the family in almost every society and experience serious psychological difficulties in line with this role. These psychological difficulties may develop due to the pathological relationships that women have, especially with their family members. In this context, the study aims to examine the mental health states of housewives within the framework of codependence and self-perceptions.

The effect of the communication skills psychoeducation program on the communication skills and self-esteem of the care personnel working in a rehabilitation center.

Purpose: The study was conducted to determine the effect of the communication skills psychoeducation program on the self-esteem and communication skills of the care staff working in a rehabilitation center.

Material And Method: The sample was 61 in the study, which was conducted in a quasi-experimental way with a single group pretest, posttest and follow-up pattern.

Finding: At the end of the psychoeducation program, it was determined that the psychoeducation has a positive effect on the self-esteem and communication skills of the care staffs.

Pharmacogenetic algorithm for predicting daily dose of warfarin in Caucasian patients of Czech origin.

Objectives: Warfarin use is limited by a low therapeutic index and significant interindividual variability of the daily dose. The most important factor predicting daily warfarin dose is individual genotype, polymorphisms of genes (warfarin metabolism) and (sensitivity for warfarin). Algorithms using clinical and genetic variables could predict the daily dose before the initiation of therapy.

The Combined Effect of APOE and BDNF Val66Met Polymorphisms on Spatial Navigation in Older Adults.

Background: The apolipoprotein E (APOE) ɛ4 allele is associated with episodic memory and spatial navigation deficits. The brain-derived neurotrophic factor (BDNF) Met allele may further worsen memory impairment in APOEɛ4 carriers but its role in APOEɛ4-related spatial navigation deficits has not been established.

Objective: We examined influence of APOE and BDNF Val66Met polymorphism combination on spatial navigation and volumes of selected navigation-related brain regions in cognitively unimpaired (CU) older adults and those with amnestic mild cognitive impairment (aMCI).

Progestin type affects the increase of heparanase level and procoagulant activity mediated by the estrogen receptor.

Study Question: Does progestin have an effect on heparanase level and procoagulant activity?

Summary Answer: Progestin increases the heparanase level and procoagulant activity via the estrogen receptor and the magnitude of the effect depends on the progestin type.

What Is Known Already: Users of combined oral contraceptives (COCs) containing third- and fourth-generation progestins have a higher risk of venous thrombosis compared to those employing second-generation progestins. Heparanase protein is capable of degrading heparan sulfate (HS) chains and enhancing activation of the coagulation system.

The effect of interpersonal relational role analysis on nursing students' anxiety levels and interpersonal problem-solving orientation.

Purpose: This study has been performed to investigate the effects of the interpersonal relational role analysis (IRRA) on the nursing students' anxiety levels and their interpersonal problem-solving orientation.

Design And Methods: This study was conducted with randomized controlled, pre-test-post-test control group design and follow-up test patterns (n = 8).

Finding: Following the practice of IRRA sessions, the findings showed that IRRA has a positive effect on the anxiety levels and interpersonal problem-solving orientations of nursing students.

Effect of St. John's wort oil and olive oil on the postoperative complications after third molar surgery: randomized, double-blind clinical trial.

Objectives: This multicenter study aimed to evaluate the effects of St. John's wort oil and virgin olive oil on the postoperative complications and compare this with chlorhexidine gluconate plus benzydamine hydrochloride mouthwash after the removal of impacted third molar.

Methods: A total of 90 patients in need of impacted third molar surgery were included in this study.

Analgesic efficacy of naproxen-codeine, naproxen+dexamethasone, and naproxen on myofascial pain: A randomized double-blind controlled trial.

Objective: To assess the effects of naproxen sodium-codeine phosphate, naproxen sodium-dexamethasone, and naproxen sodium on myofascial pain.

Methods: This randomized, double-blind prospective clinical study was conducted with patients who applied with the complaint of pain in the temporomandibular region. A total of 169 patients were randomly divided into four groups and received the following treatments: Group A: naproxen sodium 550 mg; Group B: naproxen sodium 550 mg + codeine phosphate 30 mg; Group C: naproxen sodium 550 mg + single-dose dexamethasone 8 mg, and Group D: paracetamol 500 mg.

The Effect of Age of Titanium Dental Implants on Implant Survival and Marginal Bone Resorption: A 5-Year Retrospective Follow-Up Study.

It has been demonstrated that the osteoconductivity, hydrophilicity, and biological capacity of titanium decreases over time, and this phenomenon was described as the biological aging of titanium. The aim of this study was to evaluate whether the age of sand-blasted and acid-etched (SLA) titanium dental implants (duration from the production date until the date of dental implant surgery) affects marginal bone resorption and implant survival. This nonrandom convenience-sample retrospective pilot study was carried out in 200 implants of 64 patients.

The levels of anger and aggression in street children with substance dependence.

Problem: This is a descriptive study to determine the levels of anger and aggression in street children with substance dependence.

Methods: The study was conducted between October 2013 and March 2014 with 103 street children who use substances. Personal Information Form, Aggression Scale (AS), and Trait Anger and Anger Expression Styles Scale (STAXI) were used as data collection tools.

Impact of APOE and BDNF Val66Met Gene Polymorphisms on Cognitive Functions in Patients with Amnestic Mild Cognitive Impairment.

Apolipoprotein (APOE) ɛ4 is a well-known risk factor for late-onset Alzheimer's disease (AD), but other AD-related gene polymorphisms might also be important, such as the polymorphism within the brain-derived neurotrophic factor (BDNF) gene. Carriage of BDNF Val66Met has been associated with faster cognitive decline and greater hippocampal atrophy in cognitively normal elderly. Thus, we examined the effects of the concurrent presence of APOE and BDNF polymorphisms on cognitive functions and brain morphometry in amnestic mild cognitive impairment (aMCI) patients.

Time trends in prostate cancer screening in Swiss primary care (2010 to 2017) - A retrospective study.

Introduction: Following years of controversy regarding screening for prostate cancer using prostate-specific antigen, evidence evolves towards a more restrained and preference-based use. This study reports the impact of landmark trials and updated recommendations on the incidence rate of prostate cancer screening by Swiss general practitioners.

Methods: We performed a retrospective analysis of primary care data, separated in 3 time periods based on dates of publications of important prostate-specific antigen screening recommendations.

Integrative hospital treatment in older patients to benchmark and improve outcome and length of stay - the In-HospiTOOL study.

Background: A comprehensive in-hospital patient management with reasonable and economic resource allocation is arguably the major challenge of health-care systems worldwide, especially in elderly, frail, and polymorbid patients. The need for patient management tools to improve the transition process and allocation of health care resources in routine clinical care particularly for the inpatient setting is obvious. To address these issues, a large prospective trial is warranted.