Protective and Therapeutic Capacities of Lactic Acid Bacteria Postmetabolites against Koi Herpesvirus Infection In Vitro.

Background: The accumulation of data on beneficial biological effects of probiotics and their metabolic products favors their potential use in the prevention and treatment of various malaises.

Methods: Nine postmetabolites from Lactic acid bacteria (LAB) of human or dairy origin and their antiviral activity were studied using the cytopathic effect inhibition test. The virucidal capacity, their influence on the adsorption stage of Koi herpes virus (KHV) and their preventive role against subsequent viral challenge on intact Common carp brain (CCB) cells were also determined by titration assay.

Anti-herpes virus activity of postbiotics.

Background: Recently various lactic acid bacteria (LAB) and their post-metabolites have shown many positive effects on human and animal welfare. They appear to be beneficial in different disorders and pathological conditions, including in a broad-spectrum of infectious diseases.

Aim: To estimate the anti-herpes simplex activity of 11 postbiotic samples (lysates or cell-free supernatants - CFS) produced during the fermentation of six candidate-probiotic strains isolated from Bulgarian fermented milk products.

Vibration-Induced Kinesthetic Illusions and Corticospinal Excitability Changes.

The authors' aim was to investigate the changes of corticospinal excitability during kinesthetic illusions induced by tendon vibration. Motor-evoked potentials in response to transcranial magnetic stimulation were recorded from the vibrated flexor carpi radialis and its antagonist, extensor carpi radialis. The illusions were evoked under vision conditions without feedback for the position of the wrist (open or closed eyes).

The effect of muscle vibration on short latency intracortical inhibition in humans.

Purpose: The purpose of the present study was to investigate the effect of muscle vibration (MV) on short latency intracortical inhibition (SICI) and facilitation (ICF) assessed by paired-pulse transcranial magnetic stimulation (TMS).

Methods: Nineteen right-handed healthy subjects were investigat ed without and with MV of the right extensor carpi radialis (ECR), using single- and paired-pulse TMS with interstimulus interval (ISI) of 3 and 13 ms. Intensities of the conditioning and test stimulus were 70 and 120 % of the motor threshold at rest.