Publications by authors named "Kaoru Namiki"
This case series investigates the characteristics of epidermal growth factor receptor inhibitor–induced nail changes and usefulness of the gutter method.
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- Research on the connection between psoriasis and thyroid dysfunction shows mixed results, prompting an investigation into this relationship among different types of psoriasis.
- In a study of 85 psoriasis patients, 14% were found to have thyroid dysfunction, with the highest prevalence in those with generalized pustular psoriasis (GPP).
- Patients with thyroid dysfunction had worse psoriasis severity and higher levels of inflammation (as indicated by C-reactive protein) compared to those without thyroid issues, suggesting a link between thyroid problems and psoriasis-related inflammation.
Generalized pustular psoriasis (GPP) is a systemic inflammatory disease that presents with erythema and sterile pustules, pathologically characterized by Kogoj's spongiform pustules. GPP is sometimes accompanied by mucosal involvement, and the most common lesion is on the tongue. IL36RN mutation was found to contribute to the pathogenesis of GPP especially in patients who develop GPP without a past medical history of psoriasis vulgaris.
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