Optimization of injection dose in F-FDG PET/CT based on the 2020 national diagnostic reference levels for nuclear medicine in Japan.

Objective: Recently, the national diagnostic reference levels (DRLs) in Japan were revised as the DRLs 2020, wherein the body weight-based injection dose optimization in positron emission tomography/computed tomography using F-fluoro-2-deoxy-D-glucose (F-FDG PET/CT) was first proposed. We retrospectively investigated the usefulness of this optimization method in improving image quality and reducing radiation dose.

Methods: A total of 1,231 patients were enrolled in this study.