Identification of Notch signaling pathway gene mutations as a prognostic biomarker for bladder cancer.

The authors aimed to identify Notch signaling pathway gene mutations as a prognostic biomarker for bladder cancer. First, critical Notch signaling pathway genes were screened using The Cancer Genome Atlas and validation sets. Second, immune infiltration, protein-protein interaction network, Kyoto Encyclopedia of Genes and Genomes and Gene Set Enrichment Analysis analyses were performed.

[Expression of integrin-linked kinase in prostate cancer and its significance].

Objective: To investigate the expression of integrin-linked kinase (ILK) in primary prostate cancer and its clinical significance.

Methods: The expression of ILK was analysed in 50 prostate cancer and 16 benign prostatic hyperplasia samples by immunohistochemical staining.

Results: The positive percentage of ILK was 46.