Publications by authors named "Kanyi S"

Article Synopsis
  • Trachoma is aimed for global elimination by 2030, with a focus on using IgG antibody measurements in children for monitoring and decision-making in public health programs.
  • There are no existing guidelines for using serology in trachoma control, highlighting a larger issue in the field of disease elimination and epidemiology.
  • Researchers analyzed IgG levels in 63,911 children from various regions to determine seroconversion rates and proposed a method to assess when population transmission falls below or exceeds intervention thresholds, aiding trachoma program strategies.
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Background: Hepatitis B infection is a significant global health threat contributing to healthcare worker (HCW) harm, threatening already precarious health systems.

Aim: To document self-reported hepatitis B vaccination history and serology results.

Setting: A select group of high-risk HCWs in a tertiary care hospital in Banjul, the Gambia.

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Assessing the feasibility of 2030 as a target date for global elimination of trachoma, and identification of districts that may require enhanced treatment to meet World Health Organization (WHO) elimination criteria by this date are key challenges in operational planning for trachoma programmes. Here we address these challenges by prospectively evaluating forecasting models of trachomatous inflammation-follicular (TF) prevalence, leveraging ensemble-based approaches. Seven candidate probabilistic models were developed to forecast district-wise TF prevalence in 11 760 districts, trained using district-level data on the population prevalence of TF in children aged 1-9 years from 2004 to 2022.

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Purpose: Population-based prevalence surveys are essential for decision-making on interventions to achieve trachoma elimination as a public health problem. This paper outlines the methodologies of Tropical Data, which supports work to undertake those surveys.

Methods: Tropical Data is a consortium of partners that supports health ministries worldwide to conduct globally standardised prevalence surveys that conform to World Health Organization recommendations.

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Article Synopsis
  • Trachomatous trichiasis (TT) is a painful eye problem that can cause blindness, and women are affected more than men.
  • Researchers studied data from 20 African countries to see how men and women are treated for TT and if there are differences.
  • The results showed that women are more likely to have complications after surgery and are more likely to refuse surgery, suggesting there are some gender differences in how TT is managed.
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Article Synopsis
  • Trichiasis occurs when eyelashes grow inward and touch the eyeball, potentially leading to permanent vision loss, caused mainly by repeated infections from Chlamydia trachomatis.
  • A study in The Gambia assessed the prevalence of trachomatous trichiasis (TT) through surveys in five evaluation units, using a two-stage cluster sampling method involving nearly 12,000 individuals aged 15 and older.
  • The results showed a very low prevalence of TT, with some regions reporting 0.0%, leading to The Gambia being validated in 2021 for achieving the elimination of trachoma as a public health issue, demonstrating the effectiveness of dedicated resources and political commitment in addressing the problem.
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Trachoma is the leading infectious cause of blindness in the world and has been known to be a major public health problem in The Gambia for over 60 years. Nationwide blindness surveys, including trachoma, in 1986 and 1996 provided the foundation for a comprehensive plan to implement a trachoma elimination strategy. Impact and pre-validation surveillance surveys in 2011-13 demonstrated that active trachoma was below WHO threshold for elimination but trichiasis remained a public health problem.

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Background: Global elimination of trachoma as a public health problem was targeted for 2020. We reviewed progress towards the elimination of active trachoma by country and geographical group.

Methods: In this retrospective analysis of national survey and implementation data, all countries ever known to be endemic for trachoma that had either implemented at least one trachoma impact survey shown in the publicly available Trachoma Atlas, or are in Africa were invited to participate in this study.

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Introduction: Clinically diagnosed pneumonia in children is a leading cause of paediatric hospitalisation and mortality. The aetiology is usually bacterial or viral, but malaria can cause a syndrome indistinguishable from clinical pneumonia. There is no method with high sensitivity to detect a bacterial infection in these patients and, as result, antibiotics are frequently overprescribed.

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Background: Kidney transplantation is the renal replacement therapy of choice for end stage renal disease. To ensure safety regular audit of the donation process is necessary. The aim of this study was to assess the evaluation of potential living related kidney donors and document their outcomes following nephrectomy.

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Background: The Gambia's National Eye Health Programme has made a concerted effort to reduce the prevalence of trachoma. The present study had two objectives. The first was to conduct surveillance following mass drug administrations to determine whether The Gambia has reached the World Health Organization's (WHO) criteria for trachoma elimination, namely a prevalence of trachomatous inflammation-follicular (TF) of less than 5% in children aged 1 to 9 years.

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