Low cost combination of DCIP and MCV was better than that of DCIP and OF in the screening for hemoglobin E.

Objective: To evaluate hemoglobin E screening tests in a large scale of cases.

Material And Method: A cross-sectional descriptive study was conducted Whole blood obtained from subjects was evaluated for CBC, OF, DCIP, and hemoglobin typing.

Results: Five hundred twenty seven hemoglobin E and 280 reference subjects participated.