Publications by authors named "Kanwal Farooqi"

Article Synopsis
  • * Most CMR research in children consists of small studies, making it hard to draw strong conclusions about their heart health.
  • * The publication discusses challenges faced in PCHD CMR research and offers guidance for developing larger, collaborative studies to improve understanding and care for these patients.
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Ventricular septation of the double-inlet ventricle is a largely abandoned operation due to poor historical outcomes. However, there has been renewed interest in septation as an alternative to Fontan palliation given its long-term sequelae. As one of the few centers to revisit septation in the early 1990s, our institution has long-term data on a series of patients with a double-inlet ventricle who underwent biventricular repair.

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Article Synopsis
  • The study examined trends in cardiac CT (CCT) usage among pediatric and congenital heart disease (CHD) patients by conducting a survey across North American pediatric cardiology centers in 2022, reflecting on practices from 2011 to 2021.
  • Results indicated a significant increase in CCT performance, with 98% of centers conducting CCT in 2021 compared to 73% in 2011, and a notable rise in centers performing over 100 CCTs annually.
  • Despite the increase, there is considerable variation in CCT practices among centers regarding technology use, staffing, and educational training for fellows, and common barriers to CCT usage include concerns about radiation exposure and anesthesia needs.
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Article Synopsis
  • Early career professionals in Cardiovascular Magnetic Resonance (CMR) encounter specific challenges when building their careers.
  • The Society for Cardiovascular Magnetic Resonance (SCMR) has enhanced its early career section to support the development of future leaders in the field.
  • The paper discusses the obstacles faced by budding CMR professionals and emphasizes the need for societal initiatives to promote their professional growth and ensure the ongoing advancement of CMR as a global imaging technique.
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As a result of increasing adoption of imaging screening, the number of adult patients with a diagnosis of anomalous aortic origin of the coronary arteries (AAOCA) has grown in recent years. Existing guidelines provide a framework for management and treatment, but patients with AAOCA present with a wide range of anomalies and symptoms that make general recommendations of limited applicability. In particular, a large spectrum of interventions can be used for treatment, and there is no consensus on the optimal approach to be used.

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As a result of increasing adoption of imaging screening, the number of adult patients with a diagnosis of anomalous aortic origin of the coronary arteries (AAOCA) has grown in recent years. Existing guidelines provide a framework for management and treatment, but patients with AAOCA present with a wide range of anomalies and symptoms that make general recommendations of limited applicability. In particular, a large spectrum of interventions can be used for treatment, and there is no consensus on the optimal approach to be used.

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Objectives: The case definition for multisystem inflammatory syndrome in children (MIS-C) is broad and encompasses symptoms and signs commonly seen in children with fever. Our aim was to identify clinical predictors that, independently or in combination, identify febrile children presenting to the emergency department (ED) as low risk for MIS-C.

Methods: We conducted a retrospective single-center study of otherwise healthy children 2 months to 20 years of age presenting to the ED with fever and who had a laboratory evaluation for MIS-C between April 15, 2020, and October 31, 2020.

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Multicenter studies in pediatric cardiovascular magnetic resonance (CMR) improve statistical power and generalizability. However, a structured process for identifying important research topics has not been developed. We aimed to (1) develop a list of high priority knowledge gaps, and (2) pilot the use of a wiki survey to collect a large group of responses.

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A fetal cardiology consultation involves using two-dimensional drawings to explain the cardiac anatomy which can result in inherent variation in how the congenital heart disease (CHD) is conveyed. In this pilot study, we incorporated three-dimensional printed (3DP) models into fetal counseling to demonstrate feasibility and evaluate the impact on parental knowledge, understanding, and anxiety. Parents with a prenatal diagnosis of a muscular ventricular septal defect (VSD) and/or coarctation of aorta were enrolled.

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This review aims to summarize key articles published in the Journal of Cardiovascular Computed Tomography (JCCT) in 2022, focusing on those that had the most scientific and educational impact. The JCCT continues to expand; the number of submissions, published manuscripts, cited articles, article downloads, social media presence, and impact factor continues to grow. The articles selected by the Editorial Board of the JCCT in this review highlight the role of cardiovascular computed tomography (CCT) to detect subclinical atherosclerosis, assess the functional relevance of stenoses, and plan invasive coronary and valve procedures.

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Article Synopsis
  • The study conducted a meta-analysis on the outcomes of Ross/Ross-Konno procedures in neonates and infants, adhering to PRISMA guidelines and using various databases to gather relevant studies.
  • The analysis included 587 patients and discovered an early mortality rate of 18.3% and a late mortality rate of 9.7%, with significant variability in outcomes among the studies.
  • The findings indicate a notable risk associated with these procedures, emphasizing the need for skilled surgical practices and careful selection of patients, along with the call for further multicenter research.
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Background: Multisystem inflammatory syndrome in children (MIS-C) is a severe life-threatening manifestation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection that often presents with acute cardiac dysfunction and cardiogenic shock. While recovery from acute illness is excellent, the long-term myocardial impact is unknown.

Objective: To compare cardiac MRI findings in children 6-9 months after their hospitalization with MIS-C against MRI findings in healthy controls to assess for residual myocardial disease.

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Article Synopsis
  • - The study focuses on the outcomes of tricuspid valve (TV) surgery in pediatric patients with non-Ebstein congenital TV lesions, aiming to identify surgical indications, results, and prognostic factors.
  • - A total of 85 patients were analyzed, primarily with isolated tricuspid regurgitation; surgeries included TV repairs and replacements, with no in-hospital mortality and a follow-up period of around 3.3 years.
  • - Factors such as being younger than 12 years and having significant mitral valve regurgitation were found to increase the risk of needing further surgery or experiencing serious valve issues post-operation.
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Cardiac computed tomography (CCT) has increasingly been used in the assessment of both children and adults with congenital heart disease (CHD), in part due to advances in CCT technology and an increased prevalence of adults with palliated CHD. It serves as a complimentary modality to echocardiography, cardiac magnetic resonance imaging and cardiac catheterization. CCT can provide unique diagnostic information, is less invasive and less likely to require sedation compared to other modalities.

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Congenital heart disease (CHD) is often comprised of complex three-dimensional (3D) anatomy that must be well understood to assess the pathophysiological consequences and guide therapy. Thus, detailed cardiac imaging for early detection and planning of interventional and/or surgical treatment is paramount. Advanced technologies have revolutionized diagnostic and therapeutic practice in CHD, thus playing an increasing role in its management.

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The acute manifestations and short-term outcomes of multisystem inflammatory syndrome (MIS-C) have been extensively described; however, our understanding of the longitudinal outcomes associated with this condition continue to evolve. Here we review the existing literature on outcomes of MIS-C up to 1 year following diagnosis and summarize current published expert recommendations for management and follow up of these patients.

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This review aims to summarize original articles published in the Journal of Cardiovascular Computed Tomography (JCCT) for the year 2021, focusing on those that had the most scientific and educational impact. The JCCT continues to expand; the number of submissions, published manuscripts, cited articles, article downloads, social media presence, and impact factor continues to increase. The articles selected by the Editorial Board of the JCCT in this review focus on coronary artery disease, coronary physiology, structural heart disease, and technical advances in cardiovascular CT.

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Advanced imaging is often used to supplement clinical information in guiding management for patients with heart failure. 3 dimensional (3D) imaging datasets allow for a better understanding of the relevant cardiac spatial anatomic relationships. 3D printing technology takes this one step further and allows for the creation of patient-specific physical cardiac models.

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Background Multisystem Inflammatory Syndrome in Children (MIS-C) is a severe life-threatening manifestation of SARS-CoV-2 infection. Acute cardiac dysfunction and resultant cardiogenic shock are common in children with MIS-C. While most children recover rapidly from acute illness, the long-term impact on the myocardium and cardiac function is unknown.

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Background: In spring 2020, a novel hyperinflammatory process associated with severe acute respiratory syndrome coronavirus 2 multisystem inflammatory syndrome in children (MIS-C) was described. The long-term impact remains unknown. We report longitudinal outcomes from a New York interdisciplinary follow-up program.

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Article Synopsis
  • A 3-year-old child with Loeys-Dietz Syndrome (LDS) had a small patent ductus arteriosus and a dilated aorta but showed no symptoms.
  • During routine heart imaging, a large ductal aneurysm was discovered, which was successfully removed.
  • This case highlights the importance of advanced imaging techniques for monitoring and managing patients with LDS.
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Heart failure and neoaortic dilation are common long-term complications in patients with hypoplastic left heart syndrome after single-ventricle palliation. Orthotopic heart transplantation and concomitant transverse aortic arch replacement can be performed safely and effectively. The addition of preoperative three-dimensional modelling can supplement operative planning, facilitate intraoperative execution, and optimize clinical outcomes.

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