Correlation of Exercise and Rest Tc-99m MIBI Lung/heart Ratio at Different Areas of Lung with Left Ventricular Ejection Fraction in Patients with Coronary Artery Disease.

Increased lung uptake of thallium-201 (Tl) and technetium-99m-methoxyisobutyl isonitrite (Tc-MIBI) in myocardial perfusion imaging has been proved as a reliable marker of left ventricular dysfunction. The goal of this study was to evaluate the lung uptake at the various areas of both the right and left lung (ie, right lung base and both lung apices) and its correlation with the left ventricular dysfunction by calculating lung-to-heart (L/H) uptake ratio in exercise and rest Tc-sestamibi myocardial perfusion. There were a total of 63 patients (10 female, 53 male: age range from 30-75 years, mean age 45.