Postprandial blood glucose response to grape seed extract in healthy participants: A pilot study.

Background: The consumption of a high carbohydrate diet may be associated with an increased risk of type 2 diabetes and obesity. Previous studies in vitro have revealed that grape seed extract (GSE) inhibited the intestinal α-glucosidases and α-pancreatic amylase that may delay carbohydrate digestion and absorption, resulting in the suppression of postprandial glycemia. The objective of the study was to assess whether consumption of GSE together with high carbohydrate meal affects postprandial glycemia in healthy participants.