Urinary dengue NS1 detection on Au-decorated ZnO nanowire platform.

Biodetection for non-invasive diagnostics of fluids, especially urine, remains a challenge to scientists due to low target concentrations. And biological complexes of the detection target may contain contaminants that also interfere with any assay. Dengue non-structural 1 protein (Dengue NS1) is an important biomarker for dengue hemorrhagic fever and dengue shock syndrome.

Benzimidazole-triazole ligands with pendent triazole functionality: unexpected formation and effects on copper-catalyzed aerobic alcohol oxidation.

A series of benzimidazole-triazole ligands (NN') having a pendent triazole arm with different triazole substituents including CHPh (3a), cyclo-CH (3b), and CHSiMe (3c) were obtained in moderate yields from Cu-catalyzed oxidative C-N cyclization of the respective amine-triazole compounds N,N'-bis((1-R-1,2,3-triazol-4-yl)methyl)benzene-1,2-diamine (2a-2c). Treatment of CuCl with one equiv. of the benzimidazole-triazole ligands afforded the corresponding Cu complexes with the empirical formula of Cu(NN')Cl (4a-4c).