The study develops polyamine-functionalized graphene oxide-supported NiCoS nanomaterial using a metal-organic framework (MOF). This modification adds free amines and oxygen functionality to the graphene oxide electrode surface, resulting in the decrease in the 2 theta value from 11.2 to 7.
View Article and Find Full Text PDFUnlabelled: is a multidrug-resistant fungal pathogen with a propensity to colonize humans and persist on environmental surfaces. invasive fungal disease is being increasingly identified in acute and long-term care settings. We have developed a prototype cartridge-based surveillance assay (CaurisSurV cartridge; "research use only") that includes integrated sample processing and nucleic acid amplification to detect from surveillance skin swabs in the GeneXpert instrument and is designed for point-of-care use.
View Article and Find Full Text PDFWe report a series of molecular dynamics (MD) simulations of up to a microsecond combined simulation time designed to probe epigenetically modified DNA sequences. More specifically, by monitoring the effects of methylation and hydroxymethylation of cytosine in different DNA sequences, we show, for the first time, that DNA epigenetic modifications change the molecule's dynamical landscape, increasing the propensity of DNA toward different values of twist and/or roll/tilt angles (in relation to the unmodified DNA) at the modification sites. Moreover, both the extent and position of different modifications have significant effects on the amount of structural variation observed.
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