Carbon quantum dot with co-doped nitrogen and phosphorus for tazettine ratiometric fluorescent sensing.

An overdose of tazettine (TZ) has toxic side effects, which makes it extremely important to rapidly and subtly determine the TZ. In this study, double-emitting, nitrogen-phosphorus co-doped carbon quantum dots (N,P-CQDs) were prepared using cis-butenedioic acid, phosphoric acid, and p-phenylenediamine. An effective inner filter effect (IFE) can occur between TZ and N,P-CQDs, resulting in their fluorescence quench.

Electrochemiluminescence resonance energy transfer between a Ru-ZnMOF self-enhanced luminophore and a double quencher ZnONF@PDA to detect NSE.

The construction of advanced systems capable of accurately detecting neuron-specific enolase (NSE) is essential for rapidly diagnosing small-cell lung cancer. In this study, an electrochemiluminescence (ECL) resonance energy transfer immunosensor was proposed for the ultra-sensitive detection of NSE. The co-reactants CO and Ru(bpy) were integrated to form a self-enhanced ECL luminophore (Ru-ZnMOF) as the ECL donor.

Au@NiFeMOFs as the signal quencher of Au@g-CNNSs composite for sensitive "on-off" electrochemiluminescence immunosensing of beta-2-microglobulin.

In this study, an electrochemiluminescence resonance energy transfer (ECL-RET) immunosensor was constructed to detect beta-2-microglobulin (B2M). As a donor-acceptor pair, a carbon nitride nanosheet modified with gold nanoparticles (Au@g-CNNSs) and a nickel- and iron-based organic framework modified with gold nanoparticles (Au@NiFeMOFs) were prepared. The sandwich immunosensor was successfully constructed so that ECL-RET occurred between Au@NiFeMOFs and Au@g-CNNSs.

Aggregation-Induced Electrochemiluminescence Based on a Zinc-Based Metal-Organic Framework and a Double Quencher Au@UiO-66-NH for the Sensitive Detection of Amyloid β 42 Resonance Energy Transfer.

A novel sandwich electrochemiluminescence (ECL) biosensor based on aggregation-induced electrochemiluminescence resonance energy transfer (AIECL-RET) was designed for the sensitive detection of amyloid β42 (Aβ42). The synthesized silver nanoparticle-functionalized zinc metal-organic framework (Ag@ZnPTC) and gold nanoparticle-functionalized zirconium organic framework (Au@UiO-66-NH) were used as the ECL donor and acceptor, respectively. AgNPs were generated on the surface of ZnPTC, which further improved the ECL intensity and the loading of antibody 1 (Ab1).