Publications by authors named "Kanjilal S"

The prevailing consensus is that the sequential sharing of nonlocality in a Bell experiment requires generalized unsharp measurements, given that a sharp measurement inevitably destroys the entanglement of the shared state. In contrast, a recent work [A. Steffinlongo and A.

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In infections in men eligible for doxycycline post-exposure prophylaxis (doxy-PEP), tetracycline non-susceptibility is more prevalent than in the overall population and is associated with resistance to trimethoprim-sulfamethoxazole and clindamycin. Doxy-PEP may select for multi-drug resistance, underscoring the importance of surveillance.

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Background: Uncomplicated urinary tract infection (UTI) is a common indication for outpatient antimicrobial therapy. National guidelines for the management of uncomplicated UTI were published by the Infectious Diseases Society of America in 2011, however it is not fully known the extent to which they align with current practices, patient diversity, and pathogen biology, all of which have evolved significantly in the time since their publication.

Objective: We aimed to re-evaluate efficacy and adverse events for first-line antibiotics (nitrofurantoin, and trimethoprim-sulfamethoxazole), versus second-line antibiotics (fluoroquinolones) and versus alternative agents (oral β-lactams) for uncomplicated UTI in contemporary clinical practice by applying machine learning algorithms to a large claims database formatted into the Observational Medical Outcomes Partnership (OMOP) common data model.

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  • - The study investigates the feasibility of measuring the extent of resection (EOR) and residual tumor volume (RTV) in glioma patients using MRI in resource-limited healthcare settings, finding it feasible in only 31% of cases.
  • - It shows that while volumetric analysis, which is more precise than surgeons’ estimates, does not correlate significantly with patient survival, factors like tumor grade and postoperative functional status are more impactful for survival outcomes.
  • - The research highlights logistical challenges in implementing routine volumetric assessments in developing countries, suggesting a need for better resource allocation in neurosurgical practices.
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  • Congenital spondylolisthesis is a condition in which there is a defect in the spine, often affecting children and characterized by varying degrees of spinal misalignment mostly at the L5-S1 region.
  • A study analyzed 22 patients over three years, finding that most had high-grade listhesis and reported significant improvements in pain and disability after surgical intervention.
  • The research concluded that while surgery is challenging, it can effectively alleviate symptoms, with non-reductive fixation being a viable option in certain cases to prevent complications during surgery.
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Aneurysms of the distal anterior cerebral artery (DACA) are rare but surgically challenging. Despite a known therapeutic implication of the aneurysm location on the DACA territory, the literature is unclear about its clinical and prognostic significance. Our surgical experience over the last 5 years was reviewed to compare the clinical, operative, and outcome characteristics between aneurysms located below the mid portion of the genu of the corpus callosum (called proximal aneurysms) to those distal to this point (called distal aneurysms).

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  • * Out of 637 aneurysm surgeries, 32 involved re-ruptures, with 75% of patients alive after an average follow-up of 36 months, despite a mean modified Rankin Score (mRS) indicating moderate disability.
  • * Early re-ruptures were linked to worse outcomes, with poor preoperative clinical grades forecasting long-term prognosis, revealing that severe cases may not benefit from surgical intervention.
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Background: Many hospitals have scaled back measures to prevent nosocomial SARS-CoV-2 infection given large decreases in the morbidity and mortality of SARS-CoV-2 infections for most people. Little is known, however, about the morbidity and mortality of nosocomial SARS-CoV-2 infections for hospitalized patients in the Omicron era.

Objective: To estimate the effect of nosocomial SARS-CoV-2 infection on hospitalized patients' outcomes during the pre-Omicron and Omicron periods.

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Background:  Surgical resection is the cornerstone of treatment for low-grade tumors, albeit total excision is beneficial. As the thalamus is surrounded by vital neurovascular system, lesions here present a surgical challenge.

Method: This article aims to demonstrate the trans-temporal, trans-choroidal fissure approach's effective surgical therapy on patients with thalamic lesions.

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Background: Encephalocele represent a group of disorders which is characterised by extracranial herniation of the leptomeninges, brain, and CSF through a structural defect in the cranium. They are usually associated with other intracranial anomalies which may impact the neurological development.

Aim: This study aimed to assess the predictors of neurological development of patients undergone surgical excision of occipital encephalocele.

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  • The rise of antimicrobial resistant (AMR) infections poses a significant global health danger, influenced by complex factors, including socioeconomic conditions.
  • A study in the Dallas-Fort Worth area analyzed patient data from 2015 to 2020, linking bacterial culture results to socioeconomic indices to understand AMR patterns.
  • Findings indicated that regions with high deprivation levels had higher AMR rates, suggesting that improving socioeconomic factors could help reduce AMR spread.
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Objectives: The determinants of progression-free survival (PFS) and overall survival (OS) for higher-grade meningiomas have not been clearly established and to summarize the long-term clinical outcome for patients with grade 2 or 3 meningioma and assess the PFS and OS factors.

Materials And Methods: The study included all individuals, who had undergone surgical removal of cerebral meningiomas between 2005 and 2020 and whose histological results suggested a World Health Organization (WHO) grade 2 or grade 3 diseases. Kaplan-Meier curves are plotted to examine tumor control and OS after the follow-up.

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The clinical microbiology laboratory generates a huge amount of high-quality data that play a vital role in clinical care. With proper extraction, cleaning, analysis, and validation pipelines, these data can serve multiple other purposes that include supporting laboratory operations, understanding local epidemiology, informing hospital-specific policies, and public health surveillance. In this review, I use one of the core activities of the microbiology laboratory, antimicrobial susceptibility testing (AST), to illustrate several potential applications of next-generation data analytics.

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Introduction: Traditional large craniotomies have been the standard for aneurysm surgery. However, minimally invasive "keyhole" approaches have gained popularity for aneurysm clipping in recent years. This study focuses on Supra-Orbital Keyhole Approach (SOKHA),its use in clipping of aneurysms of the anterior Circle of Willis.

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Objective: Many providers use severe acute respiratory coronavirus virus 2 (SARS-CoV-2) cycle thresholds (Ct values) as approximate measures of viral burden in association with other clinical data to inform decisions about treatment and isolation. We characterized temporal changes in Ct values for non-SARS-CoV-2 respiratory viruses as a first step to determine whether cycle thresholds could play a similar role in the management of non-SARS-CoV-2 respiratory viruses.

Design: Retrospective cohort study.

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Background: The exact reason of nonaneurysmal subarachnoid hemorrhage (SAH) is an enigma. The aim of this study is to identify if type III deep cerebral venous drainage is exclusively prevalent in patients with nonaneurysmal SAH and to enumerate the predictors of poorer outcome in these patients.

Methods: All patients of age >18 years, presented at our centre with spontaneous SAH on noncontrast computed tomography head and were divided into 2 groups, aneurysmal and nonaneurysmal SAH after 4-vessel DSA.

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Objective: Minimally invasive spine surgery is rapidly gaining popularity because of its versatile nature. Traditionally, prolapsed disc has been the most common disease targeted using this technique. However, its usefulness for various other diseases has also been shown in studies.

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