Publications by authors named "Kanishka Uttam Chandani"

Background: Medicaid expansion afforded increased healthcare access to low-income Americans contributing to a positive impact on cancer outcomes. However, it is unclear if these benefits were mainly due to enhanced access to cancer screening and earlier diagnosis versus access to cancer treatment METHODS: The National Cancer Database (NCDB) was queried between 2010-2021 for Medicaid and uninsured patients with GI malignancies. Patients were stratified by screenable (SGI) and non-screenable (NGI) cancers and expansion state (ES) categories: early (EES) and late (LES) adopters, and non-expansion state (NES) cohorts.

View Article and Find Full Text PDF

Background: Poly (ADP-ribose) polymerase inhibitors (PARPis) are approved as first-line therapies for breast cancer gene ()-positive, human epidermal growth factor receptor 2-negative locally advanced or metastatic breast cancer. They are also effective for new and recurrent ovarian cancers that are - or homologous recombination deficiency (HRD)-positive. However, data on these mutations and PARPi use in the Middle East are limited.

View Article and Find Full Text PDF

: Non-Hodgkin lymphoma (NHL) has the sixth-highest malignancy-related mortality in the United States (US). However, inequalities exist in access to advanced care in specific patient populations. We aim to study the racial disparities in major adverse cardiovascular and cerebrovascular events (MACCEs) in NHL patients.

View Article and Find Full Text PDF
Article Synopsis
  • - Cardiac amyloidosis (CA) is a major condition that leads to heart issues, specifically heart failure with preserved ejection fraction (HFpEF), due to the buildup of amyloid fibrils in the heart.
  • - Its prevalence in older patients is becoming more recognized, and new diagnostic techniques like the Tc-PYP scan and treatments such as tafamidis have increased awareness and understanding of the disease.
  • - The management of cardiac complications caused by CA is becoming increasingly important, focusing on issues like heart failure and arrhythmias, as well as reviewing recent advances in diagnosis and treatment strategies.
View Article and Find Full Text PDF