Non-Optical, Label-free Electrical Capacitance Imaging of Microorganisms.

Unlabelled: Many fundamental insights into microbiology have come from imaging, which is typically synonymous with optical techniques. However, the sample preparation needed for many optical microscopy methods such as labeling, fixing, or genetic modification, limits the range of species and environments we can investigate. Here we demonstrate the use of electrical capacitance measurements as a non-optical method for imaging live microbial samples.

Electrical Capacitance Tomography of Cell Cultures on a CMOS Microelectrode Array.

Electrical capacitance tomography (ECT) can be used to predict information about the interior volume of an object based on measured capacitance at its boundaries. Here, we present a microscale capacitance tomography system with a spatial resolution of 10 microns using an active CMOS microelectrode array. We introduce a deep learning model for reconstructing 3-D volumes of cell cultures using the boundary capacitance measurements acquired from the sensor array, which is trained using a multi-objective loss function that combines a pixel-wise loss function, a distribution-based loss function, and a region-based loss function to improve model's reconstruction accuracy.

Microscale 3-D Capacitance Tomography with a CMOS Sensor Array.

Electrical capacitance tomography (ECT) is a non-optical imaging technique in which a map of the interior permittivity of a volume is estimated by making capacitance measurements at its boundary and solving an inverse problem. While previous ECT demonstrations have often been at centimeter scales, ECT is not limited to macroscopic systems. In this paper, we demonstrate ECT imaging of polymer microspheres and bacterial biofilms using a CMOS microelectrode array, achieving spatial resolution of 10 microns.

Programmable Electrochemical Stimulation on a Large-Scale CMOS Microelectrode Array.

In this paper we present spatio-temporally controlled electrochemical stimulation of aqueous samples using an integrated CMOS microelectrode array with 131,072 pixels. We demonstrate programmable gold electrodeposition in arbitrary spatial patterns, controllable electrolysis to produce microscale hydrogen bubbles, and spatially targeted electrochemical pH modulation. Dense spatially-addressable electrochemical stimulation is important for a wide range of bioelectronics applications.

Tac-Trainer: A Visual Analytics System for IoT-based Racket Sports Training.

Conventional racket sports training highly relies on coaches' knowledge and experience, leading to biases in the guidance. To solve this problem, smart wearable devices based on Internet of Things technology (IoT) have been extensively investigated to support data-driven training. Considerable studies introduced methods to extract valuable information from the sensor data collected by IoT devices.

Super-Resolution Electrochemical Impedance Imaging With a 512 × 256 CMOS Sensor Array.

Super-resolution imaging is a family of techniques in which multiple lower-resolution images can be merged to produce a single image at higher resolution. While super-resolution is often applied to optical systems, it can also be used with other imaging modalities. Here we demonstrate a 512 × 256 CMOS sensor array for micro-scale super-resolution electrochemical impedance spectroscopy (SR-EIS) imaging.