Publications by authors named "Kangli Yin"
Article Synopsis
- Peripheral arterial disease (PAD) is a serious condition caused by narrowed arteries that leads to reduced blood flow, primarily resulting in symptoms like leg pain during walking.
- The study aims to assess the efficacy and safety of Ruanjian Qingmai granules, a traditional Chinese medicine, in treating symptomatic PAD, with more than 600,000 patients having reportedly benefited from it over the last thirty years.
- Conducted across nine hospitals in Shanghai, the trial will compare the effects of Ruanjian Qingmai granules to a placebo over 16 weeks, measuring outcomes such as pain-free walking distance and quality-of-life scores.
Introduction: Peripheral arterial disease (PAD) affects approximately 236 million people worldwide. Therefore, this study aimed to investigate the relationship between CYP2C19 genotype polymorphisms and clopidogrel resistance (CR) following revascularization in patients with PAD.
Materials And Methods: In total, 345 patients who underwent PAD revascularization were monitored for five years and risk factors for ischemic events were identified.
Unraveling shared risk factors for diabetic foot ulcer: a comprehensive Mendelian randomization analysis.
BMJ Open Diabetes Res Care
November 2023
Introduction: Diabetic foot ulcer (DFU) stands as a severe diabetic lower extremity complication, characterized by high amputation rates, mortality, and economic burden. We propose using Mendelian randomization studies to explore shared and distinct risk factors for diabetic lower extremity complications.
Research Design And Methods: We selected uncorrelated genetic variants associated with 85 phenotypes in five categories at the genome-wide significance level as instrumental variables.
Introduction: There are few studies on the relationship between the occurrence of clopidogrel-related high residual platelet reactivity (HRPR) and estimated glomerular filtration rate (eGFR) at admission in patients with ischemic stroke. The aim of this study was to investigate the possible relationship between the two.
Methods: Patients who were hospitalized and diagnosed with acute ischemic stroke were recruited from July 1, 2017, to June 30, 2018, at Shanghai TCM-Integrated Hospital.
Background: Prion diseases are a group of degenerative nerve diseases that are caused by infectious prion proteins or gene mutations. In humans, prion diseases result from mutations in the prion protein gene (PRNP). Only a limited number of cases involving a specific PRNP mutation at codon 196 (E196A) have been reported.
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