A safe and robust in-situ polymerized cementitious electrolyte coupled with NiCoS@CuCoS electrode for superior load-bearing integrated electrochemical capacitor.

Load bearing/energy storage integrated devices (LEIDs) featuring cementitious electrolytes have become ideal for large-scale energy storage. Nevertheless, the progression of LEIDs is still in its nascent phase and considerable endeavors concerning cementitious electrolytes and electrode materials are necessary to further boost the charge storage ability. Here, we propose a facile synchronous reaction method for preparing sodium acrylate (SA)-based in-situ polymerized cementitious electrolyte.

METTL3-mediated m6A methylation of C1qA regulates the Rituximab resistance of diffuse large B-cell lymphoma cells.

Rituximab has been incorporated into the standard treatment regimen for diffuse large B-cell lymphoma (DLBCL), and induces the death of tumor cells via complement-dependent cytotoxicity (CDC). Unfortunately, the resistance of DLBCL cells to Rituximab limits its clinical usefulness. It remains unclear whether the complement system is related to Rituximab resistance in DLBCL.

Different gene alterations in patients with non-small-cell lung cancer between the eastern and southern China.

Geographical differences are conspicuous in lung cancer, and the distinct molecular features of lung tumor between Western patients and Asian patients have been demonstrated. However, the etiology of non-small-cell lung cancer (NSCLC) and the distribution of associated molecular aberrations in China have not been fully elucidated. The mutational profiles of 12 lung cancer-related genes were investigated in 85 patients from eastern China and 88 patients from southern China who had been histologically confirmed NSCLC.

MT1G Regulates c-MYC/P53 Signal to Inhibit Proliferation, Invasion and Migration and Promote Apoptosis in Colon Cancer Cells.

Introduction: Colon cancer is a common and malignant cancer featuring high morbidity and poor prognosis.

Aims: This study was performed to explore the regulatory role of MT1G in colon cancer as well as its unconcealed molecular mechanism.

Methods: The expressions of MT1G, c-MYC, and p53 were assessed with the application of RT-qPCR and western blot.

High levels of Tim-3Foxp3Treg cells in the tumor microenvironment is a prognostic indicator of poor survival of diffuse large B cell lymphoma patients.

Foxp3Treg cells display phenotypic and functional heterogeneity, which express high levels of T cell immunoglobulin and mucin-domain containing-3 (Tim-3) in the tumor microenvironment (TME) of colorectal and lung cancer. High abundance of Tim-3Foxp3Treg (TFT) cells are associated with poor prognosis in these patients. However, the expression patterns and roles of TFT cells in TME of diffuse large B cell lymphoma (DLBCL) remain to be established.

Comparison of gene mutation spectra in younger and older Chinese acute myeloid leukemia patients and its prognostic value.

Differences in the gene mutation spectra of younger and older Chinese adult AML patients and the prognostic significance of these differentially presented gene mutations are rarely reported. One hundred and thirteen newly diagnosed Chinese adults with AML, divided into groups of younger and older patients, were enrolled in this study. Bone marrow samples from the patients were analyzed using targeted next-generation sequencing with a panel of 141 genes.

Proposal of a Nomogram for Predicting Survival in Patients with Siewert Type II Adenocarcinoma of the Esophagogastric Junction After Preoperative Radiation.

Background: Preoperative radiotherapy tends to be more frequently used for patients with adenocarcinoma of the esophagogastric junction (AEG); however, the prognostic values of postoperative pathologic characteristics in these patients remain unclear. This study aimed to examine the outcomes in Siewert type II AEG patients receiving preoperative radiotherapy to identify the predictive factors for overall survival (OS).

Methods And Results: A total of 1818 AEG patients undergoing preoperative radiotherapy were reviewed.