Publications by authors named "Kang-Chen Fan"

With the increasing prevalence of age-related chronic diseases burdening healthcare systems, there is a pressing need for innovative management strategies. Our study focuses on the gut microbiota, essential for metabolic, nutritional, and immune functions, which undergoes significant changes with aging. These changes can impair intestinal function, leading to altered microbial diversity and composition that potentially influence health outcomes and disease progression.

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Background: Air pollution is recognized as a modifiable risk factor for dementia, and recent evidence suggests that improving air quality could attenuate cognitive decline and reduce dementia risk. However, studies have yet to explore the effects of improved air quality on brain structures. This study aims to investigate the impact of air pollution reduction on cognitive functions and structural brain differences among cognitively normal older adults.

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Introduction: The microbiota-gut-brain axis is implicated in Alzheimer's disease. Gut microbiota alterations in mild cognitive impairment (MCI) are inconsistent and remain to be understood. This study aims to investigate the gut microbial composition associated with MCI, cognitive functions, and structural brain differences.

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Synopsis of recent research by authors named "Kang-Chen Fan"

  • - Kang-Chen Fan's recent research focuses on understanding the interactions between gut microbiome, aging, and cognitive health, specifically the implications of gut microbial composition on age-related chronic diseases and cognitive decline.
  • - Fan has investigated the role of probiotics in supporting gut health among aging populations, emphasizing how changes in microbiota can influence nutritional and immune functions, which are essential for maintaining health.
  • - Another key area of exploration includes the effects of air pollution on cognitive aging, revealing potential links between improved air quality and cognitive function in older adults, alongside structural changes in the brain.