Facet-engineered NaNbO cubes with exposed (101) plane for enhanced lithium-ion storage.

Density functional theory (DFT) predicts superior lithium-ion diffusion the (101) plane of NaNbO. Experimental results confirm that despite a reduction in surface area, 6 μm NaNbO cubes with more (101) plane exposure exhibit enhanced Li storage, underscoring the significance of crystal facet engineering.

Vitamin D3 promotes gastric cancer cell autophagy by mediating p53/AMPK/mTOR signaling.

Vitamin D3 has the general properties of a lipid-soluble vitamin, but is also an active steroid hormone that can regulate the proliferation, apoptosis and differentiation of many tumor cells, and exerts anticancer activity against numerous malignancies. However, the mechanism underlying the effects of vitamin D3 on tumors is not fully understood. Here, we used network pharmacology and experimental approaches to explore the mechanism of vitamin D3 activity in the context of gastric cancer.

FeNbO nanochains with a five-electron transfer reaction toward high capacity and fast Li storage.

High capacity and outstanding rate performance of the FeNbO nanochain anode with both intercalation and conversion reactions for lithium-ion batteries are demonstrated. The unique one-dimensional structure and intercalation pseudocapacitive behavior of FeNbO accelerate the reaction kinetics. X-ray diffractometer measurement confirms a five-electron transfer mechanism for Li storage.

Exploring the mechanism of aloe-emodin in the treatment of liver cancer through network pharmacology and cell experiments.

Aloe-emodin (AE) is an anthraquinone compound extracted from the rhizome of the natural plant rhubarb. Initially, it was shown that AE exerts an anti-inflammatory effect. Further studies revealed its antitumor activity against various types of cancer.

CCUS development in China and forecast its contribution to emission reduction.

Nowadays environmental issues have been of great concern to the world, among which the problem of global warming caused by greenhouse gas emissions is particularly prominent. All countries in the Kyoto Protocol and the Paris Agreement have committed to control greenhouse gas emissions, and China, as the largest carbon emitter, has assumed a heavier burden. China has been striving to develop low-carbon technologies such as hydrogen, nuclear, wind, and solar energy, but the most attention should be paid to CCUS, which many scholars have high expectations that CCUS can help China reduce emissions to some extent.

Glutamate Chemical Exchange Saturation Transfer (GluCEST) MRI to Evaluate the Rapid Antidepressant Effects of Ketamine in the Hippocampus of Rat Depression Model.

Background: Ketamine is a quick acting antidepressant drug, and an accurate detection method is lacking. Ketamine's effects in a rat depression model have not previously been well explored using glutamate chemical exchange saturation transfer (GluCEST).

Purpose: To investigate the GluCEST changes of chronic unpredictable mild stress (CUMS) rats after receiving either ketamine or saline injection.

Linker Engineering of Sandwich-Structured Metal-Organic Framework Composites for Optimized Photocatalytic H Production.

While the microenvironment around catalytic sites is recognized to be crucial in thermocatalysis, its roles in photocatalysis remain subtle. In this work, a series of sandwich-structured metal-organic framework (MOF) composites, UiO-66-NH @Pt@UiO-66-X (X means functional groups), is rationally constructed for visible-light photocatalytic H production. By varying the ─X groups of the UiO-66-X shell, the microenvironment of the Pt sites and photosensitive UiO-66-NH core can be simultaneously modulated.

The mechanism of vitamin D3 in preventing colorectal cancer through network pharmacology.

Colorectal cancer (CRC) is a common cancer that cannot be detected at an early stage and is a major challenge in oncology research. Studies have shown that vitamin D3 has some anti-cancer and preventive effects on colorectal cancer, but the exact anti-cancer mechanism is not clear. We applied the relevant research methods of network pharmacology to speculate and validate the possible potential pharmacological mechanisms of vitamin D3 for the prevention of colorectal cancer, and to provide more theoretical support for the clinical anticancer effects of vitamin D3.

Exploring the mechanism of curcumin in the treatment of colon cancer based on network pharmacology and molecular docking.

Curcumin is a plant polyphenol extracted from the Chinese herb turmeric. It was found that curcumin has good anti-cancer properties in a variety of cancers, but the exact mechanism is not clear. Based on the network pharmacology and molecular docking to deeply investigate the molecular mechanism of curcumin for the treatment of colon cancer, it provides a new research direction for the treatment of colon cancer.

Analysis of the Coupling Effect and Space-Time Difference between China's Digital Economy Development and Carbon Emissions Reduction.

Previously conducted studies have established that the digital economy has a one-way inhibition effect on carbon emissions. Against this background, this paper aims to analyze the coordinated development effect of the interaction between the digital economy and carbon emissions reduction. The entropy weight method, coupling and coordination degree model, Dagum Gini coefficient and Moran's I index have been carried out as research methods in this paper.

Intelligent Manufacturing and Carbon Emissions Reduction: Evidence from the Use of Industrial Robots in China.

Driven by the information technology revolution, using artificial intelligence to promote intelligent manufacturing while achieving carbon emissions reduction is increasingly the focus of international attention. Given this, based on the fact that China's industrial manufacturing is more intelligent, this paper uses industrial sector data and robot data from 2000 to 2017 to examine the impact of intelligent manufacturing on industrial carbon dioxide emissions and to discuss its internal mechanism. The research found that intelligent manufacturing significantly inhibits carbon dioxide emissions in the industrial sectors.

Development and Validation of a Predictive Nomogram for Possible REM Sleep Behavior Disorders.

Objectives: To develop and validate a predictive nomogram for idiopathic rapid eye movement (REM) sleep behavior disorder (RBD) in a community population in Beijing, China.

Methods: Based on the validated RBD questionnaire-Hong Kong (RBDQ-HK), we identified 78 individuals with possible RBD (pRBD) in 1,030 community residents from two communities in Beijing. The least absolute shrinkage and selection operator (LASSO) regression was applied to identify candidate features and develop the nomogram.

[Panax notoginseng: a review on chemical components, chromatographic analysis, P. notoginseng extracts, and pharmacology in recent five years].

As a famous and precious Chinese medicinal material, Panax notoginseng(PN) has been commonly used for a long history in China. As reported, PN exhibits significant pharmacological actions in protecting cardiocerebral vascular system and nervous system and suppressing tumors. In recent years, with the innovation in ideas, as well as the development of methods and equipment, PN has been extensively investigated, and notable progress has been made.

Corrigendum: Systematic Characterization and Identification of Saikosaponins in Extracts From var. Using UPLC-PDA-Q/TOF-MS.

[This corrects the article DOI: 10.3389/fchem.2021.

Systematic Characterization and Identification of Saikosaponins in Extracts From Using UPLC-PDA-Q/TOF-MS.

Saikosaponins comprise a large group of chemical components present in the species that have attracted attention in the field of medicine because of their significant biological activities. Due to the high polarity, structural similarity, and the presence of several isomers of this class of components, their structural identification is extremely challenging. In this study, the mass spectrometric fragmentation pathways, UV spectral features, and chromatographic behavior of different types of saikosaponins were investigated using 24 standard substances.

Oxygen vacancies boosted the electrochemical kinetics of NbO for superior lithium storage.

The introduction of oxygen vacancies (OVs) into NbO can not only provide more active sites for lithium storage but also change the electronic structure of NbO to boost electron/ion transport kinetics. Consequently, the defective NbO exhibits high lithium storage capacity, superior rate capability, and cycling stability.

Glutamate Chemical Exchange Saturation Transfer Imaging and Functional Alterations of Hippocampus in Rat Depression Model: A Pilot Study.

Background: Adjusting abnormal glutamate neurotransmission is a crucial mechanism in the treatment of depression. However, few non-invasive techniques could effectively detect changes in glutamate neurotransmitters, and no consensus exists on whether glutamate could affect resting-state function changes in depression.

Purpose: To study the changes in glutamate chemical exchange saturation transfer (GluCEST) value in the hippocampus of rat model exposed to chronic unpredictable mild stress (CUMS), and to explore the effect of this change on the activity of hippocampal glutamatergic neurons.

Ligustroflavone ameliorates CCl-induced liver fibrosis through down-regulating the TGF-β/Smad signaling pathway.

Liver fibrosis is a pathological process characterized by excess deposition of extracellular matrix (ECM) that are mainly derived from activated hepatic stellate cells. Previous studies suggested that ligustroflavone (LF) was an ingredient of Ligustrum lucidum Ait. with activities of anti-inflammation and anti-oxidation.

Optical properties of D and S defects induced by Si/Ni ions co-implanting into Si films on insulator.

In the article, we report the photoluminescence (PL) properties of D and S defects induced by Si/Ni ions co-implanting into the top Si film of the silicon-on-insulator (SOI) wafer. Variable-temperature PL spectra of these co-implanted SOI samples indicate that the light emitting from the D defects can be observed as high as 273 K. In comparison with the other ion-implantation, the Si/Ni ion-co-implantation optimizes luminescent temperature stability of the both D and S defects and purifies the S defect type in silicon then effectively restrains the spectral broadening of the S-line in PL spectra.

Tunability in the Optical and Electronic Properties of ZnSe Microspheres via Ag and Mn Doping.

ZnSe microspheres with various Ag and Mn doping levels were prepared by the hydrothermal method using Zn(NO)·6HO and NaSeO as precursors and NH·HO as the reducing agent. The effects of Ag and Mn doping on the phase composition, morphology, and optical and electrical properties of the final products were systematically investigated. A remarkable change in morphology from microspheres with a cubic sphalerite structure to rodlike structure was observed by Ag doping, while the pristine structure was nearly unchanged via Mn doping.

Wound-healing Activity of Maxim Seed Oil on Experimentally Burned Rats.

Background: The seed oil of Maxim (ZBSO) is considered to be rich source of fatty acids, mainly oleic and linoleic acids, and has been used for the treatment of burns in Chinese medicine.

Objective: We evaluated the healing efficacy of ZBSO and explored its possible mechanism on scalded rats.

Materials And Methods: Sprague-Dawley rat models with deep second-degree burns were set up, and ZBSO (500 and 1000 μl/wound) was topically applied twice daily for 7 days and then once daily until wound healing.

Milk fatty acids profiles and milk production from dairy cows fed different forage quality diets.

Thirty lactating Holstein cows were used to investigate the effects of different forages quality on milk fatty acids (FA) profiles and production. The cows were assigned to 3 dietary treatments ( = 10 per treatment) in a randomized block design with 3 repeated measures. They were fed the experimental diets for 90 d with 3 days of collection of samples for analysis at about 27 d intervals (samples were collected on days 28, 29, 30, 58, 59, 60, 88, 89 and 90).

Inhibition of autophagy-potentiated chemosensitivity to cisplatin in laryngeal cancer Hep-2 cells.

Objective: The purposes of this study were to determine whether autophagy was involved in cisplatin (CDDP) resistance and to investigate the role of the autophagy in the regulation of chemosensitivity to CDDP in laryngeal cancer Hep-2 cells.

Methods: A WST-1 assay was performed to determine cell viability and cell proliferation. Autophagy activation and proapoptotic effects were characterized using monodansylcadaverine labeling and Hoechest staining, respectively.