Publications by authors named "Kang Chen"

An ideal green leaf-deposited pesticide formulation should offer advantages such as good water dispersibility, strong foliar affinity, sustained or controlled release of active ingredients, photostability and rain-fastness, minimal nontarget toxicity, use of nontoxic organic solvents, and degradable adjuvants. In line with this objective, we present green preparation of a colloidal pesticide formulation using optimized lysine-derived carbon dots (LysCDs)-modified CaCO (LysCDs/CaCO) particles as the carrier and abamectin (Abm) as the active ingredient. The loading capacity of abamectin in this colloidal pesticide (LysCDs/CaCO/Abm) is 1.

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The evolution of energy structure and the push for carbon neutrality have triggered an urgent call for lithium-ion batteries (LIBs). However, reclaiming end-of-life LIBs with high purity, high efficiency, and low environmental impact, particularly by eliminating chemical reagent usage and promoting a closed-loop carbon footprint, is challenging. Herein, we proposed a strategy that couples the carbon capture (CC) process with an electrochemically enhanced membrane distillation system (ECMD).

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  • Gynostemma pentaphyllum, used in teas, has three flavor types: bitter, sweet, and tasteless, but the reasons for these differences are not well understood.
  • The study employs various methods, including sensory evaluation and metabolomic analysis, to identify the structural differences in saponins that correlate with flavor, finding that sweet saponins have glucose chains while bitter ones contain rhamnose.
  • Molecular docking reveals specific amino acids in taste receptors that interact with compounds, indicating that increased rhamnose or unsaturation in saponins correlates with a more bitter taste.
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  • Antarctic krill oil (AKO) has health benefits but faces challenges in food applications due to stability issues, unpleasant flavors, and low astaxanthin bioavailability.
  • Researchers isolated Antarctic krill protein (AKPI) from krill processing by-products and combined it with gum Arabic (GA) to create microcapsules, which effectively improved AKO's limitations.
  • The optimized microcapsules showed an 80.22% encapsulation efficiency, masked the bad odor of AKO, allowed for controlled release in the digestive system, and enhanced astaxanthin retention and oxidative stability during storage.
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Megalobrama amblycephala, a main herbivorous fish with notable economic benefits in China, often faces serious challenges to its survival and growth due to hypoxia and heat caused by factors such as global warming and intensive aquaculture. To evaluate the combined effects of these stressors, we performed a two-factor crossover test to assess the impacts of simultaneous exposure to hypoxia (2 mg/L) and heat (35 °C) on oxidative stress, immunity and apoptosis in M. amblycephala.

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Purpose: To investigate the application value of the neutrophil to lymphocyte count ratio (NLR) in the prognostic analysis of intrahepatic cholangiocarcinoma (ICC) after radical resection, and to offer guidance for the individualized perioperative diagnosis and treatment of ICC.

Methods: The clinical data of 360 patients diagnosed with ICC following radical surgery were retrospectively analyzed. The cut-off value of NLR was calculated using the minimum -value method, and then divided into High-NLR (H-NLR) group and Low-NLR (L-NLR) group according to the NLR cut-off value.

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  • Pancreatic cancer can lead to severe abdominal pain, and while peripheral mechanisms have been explored, the involvement of the central nervous system, specifically the nucleus tractus solitarii (NTS), remains less understood.
  • Researchers found that in mice experiencing pancreatic cancer-induced pain, neurons in the NTS showed increased activity and excitability, alongside signs of neuroinflammation and microglia activation.
  • Intervention using a microglia inhibitor or blocking the CXCL1-CXCR2 signaling pathway significantly reduced pain symptoms, suggesting that the activation of microglia in the NTS plays a crucial role in mediating this pain response.*
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Licorice, known as the "elder statesman," is commonly used in traditional Chinese medicine (TCM) formulations. This study aims to establish a workflow combining animal and in silico experiments to elucidate the mechanisms of TCMs at both qualitative and quantitative levels. UPLC-Q-TOF-MS/MS was employed to qualitatively characterize the total components of honey-fried licorice and the plasma components after oral administration in Beagle dogs.

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Mineral nutrient deficiencies and metal ion toxicities coexist on acid soils. Phosphorus (P) deficiency in plants is generally accompanied with significant levels of leaf manganese (Mn) accumulation. However, the molecular regulatory mechanisms underpinning remain unclear.

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Background: This study aims to explore the association and determine the distinguished potential of anthropometric adiposity indices in screening for hypertension and hyperlipidaemia in the Chinese population.

Methods: A recent nationwide cross-sectional study, called the Thyroid Disorders, Iodine State, and Diabetes Epidemiological Survey (TIDE 2015-2017), provided the newest data on the relationships between anthropometric adiposity indices and hypertension and hyperlipidaemia and included 65,231 subjects. The area under the curve (AUC) was used to assess the feasibility of using these indices to distinguish hypertension and hyperlipidaemia.

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Background: To investigate the therapeutic benefits of theta burst stimulation on lower-limb motor dysfunction and balance recovery in patients with stroke.

Methods: A literature search was performed across CNKI, CBM, WanFang, VIP, PubMed, Embase, Cochrane Library, and Web of Science until November 2023. The Methodological quality of included studies was assessed by using the Cochrane risk-of-bias tool and the PEDro scale, and the meta-analysis was performed by using RevMan 5.

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Knowledge tracing is a technology that models students' changing knowledge state over learning time based on their historical answer records, thus predicting their learning ability. It is the core module that supports the intelligent education system. To address the problems of sparse input data, lack of interpretability and weak capacity to capture the relationship between exercises in the existing models, this paper build a deep knowledge tracing model DKVMN&MRI based on the Dynamic Key-Value Memory Network (DKVMN) that incorporates multiple relationship information including exercise-knowledge point relations, exercise-exercise relations, and learning-forgetting relations.

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Stylosanthes is an important forage legume in tropical areas with strong resistance to aluminum (Al) toxicity, though knowledge of mechanisms underlying this resistance remains fragmentary. We found that border-like cells (BLCs) were constitutively produced surrounding the root tips of all 54 examined Stylosanthes guianensis genotypes, but not the Stylosanthes viscose genotype TF0140. In genotypic comparisons under Al conditions, the S.

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Magnetic CuFeO was prepared with the modified sol-gel method and used for enhanced peroxymonosulfate (PMS) activation and ofloxacin (OFL) degradation. The OFL could almost degrade within 30 min at a catalyst dosage of 0.66 g/L, PMS concentration of 0.

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  • The study aimed to develop a macrophage signature to predict clinical outcomes and the effectiveness of immunotherapy in cholangiocarcinoma patients.
  • Researchers utilized machine learning methods to create the macrophage-related signature (MRS) using multiple datasets, including TCGA and immunotherapy response data.
  • The MRS was found to be a reliable predictor of patient outcomes, with high scores linked to worse prognosis and specific tumor characteristics, demonstrating its potential as a prognostic tool in cholangiocarcinoma.
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Early diagnosis of gestational diabetes mellitus (GDM) reduces the risk of adverse perinatal and maternal outcomes. At present, the value of serum adiponectin (ADP) and pregnancy-associated plasma protein A (PAPP-A) in clinical practice for the diagnosis of GDM in early pregnancy is unclear. To investigate the predictive value of serum ADP and PAPP-A in GDM.

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  • The paper explores how a flexible active ring, made up of active Brownian particles, escapes from a flat attractive surface using simulations.
  • It identifies two main mechanisms for escape: a thermal activation process at low persistence times and a force-related issue at high persistence times.
  • The study concludes that while the active ring has a complex structure, it can be effectively understood as a self-propelled Brownian particle for understanding its escape dynamics.
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One pathological feature of Alzheimer's disease (AD) is the dysregulated metal ions, e.g., zinc, copper, and iron in the affected brain regions.

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Physical activity, as a promising complementary therapy, has shown considerable potential for reducing chemotherapy-related cardiotoxicity (CTRCT) and enhancing cardiorespiratory function (CRF). This study aimed to systematically assess the effects of physical activity on CTRCT and CRF in various cancer survivors receiving chemotherapy. A systematic review and meta-analysis was conducted.

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Chemically modified nucleic acid molecules have been developed as oligonucleotide therapeutics, and its assay is critical in quality assurance. The common DNA/RNA quantification method using UV-260 nm can lack accuracy because of structure modifications and the possible formation of higher-order structure (HOS). Additionally, process-associated water and counterions affect the accuracy in gravimetric analysis.

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Aluminum (Al) toxicity is a significant limiting factor for crop production in acid soils. The functions and regulatory mechanisms of transcription factor STOP1 (Sensitive to Proton Rhizotoxicity 1) family genes in Al-tolerance have been widely studied in many plant species, except for soybean. Here, expression of GmSTOP1-3 was significantly enhanced by Al stress in soybean roots.

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Synthetic polypeptides, also known as poly(α-amino acids), have the same polyamide backbone structures as natural proteins and peptides. As an important class of biomaterials, polypeptides have been widely used because of their biocompatibility, bioactivity and biodegradability. Ring-opening polymerization of N-carboxyanhydride (NCA) is a classical and widely used method for the synthesis of polypeptides.

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