Publications by authors named "Kandasamy Veerapandiyan"

Article Synopsis
  • * Two flavonoids, procyanidin B2 and luteolin, showed better interaction and stability as aromatase inhibitors compared to the commercial drug letrozole through various modeling and simulation techniques.
  • * Experimentation on zebrafish indicated that these compounds could effectively reduce aromatase levels in ovarian tissues, suggesting their potential use in treating infertility related to PCOS.
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L. is a traditional medicinal plant containing a potential homoisoflavonoid, bonducellin, with therapeutic values against polycystic ovary syndrome, oxidative damage, pathogenic bacteria, irregular menstrual cycle, ovarian cancer and diabetes. Owing to the multi-therapeutic properties of bonducellin, knowledge of its biosynthetic pathway genes will help understand its regulatory mechanism and thus improve the yield.

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Ethnopharmacological Relevance: Caesalpinia bonduc (L.) Roxb. [Family: Fabaceae (Caesalpiniaceae)], known as bonduc nut or fever nut, has been used in India for many years to treat fever, inflammation, diabetes, cardiovascular disorder, cancer and also for birth control.

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