Extract and its Bioactive Component Cinnamaldehyde Show Anti-Tumor Effects Inhibition of Multiple Cellular Pathways.

is a tropical plant with traditional medicinal significance that possesses antimicrobial, antifungal, anti-parasitic, and anti-tumor properties. Here, we have elucidated the anti-tumor effects of extract (CZE) and its bioactive compound cinnamaldehyde (CIN) on oral cancer and elucidated underlying molecular mechanisms. Anti-tumor activities of CZE and CIN were demonstrated by various experiments on oral cancer cells (SCC-4, SCC-9, SCC-25).