Publications by authors named "Kanapadinchareveetil Sreelekha"

Chemical acaricides are widely used for the effective control of ticks in India. The synthetic pyrethroids, are one of the most popular chemical acaricides with selective neurotoxic potential. Flumethrin is a type II synthetic pyrethroid used extensively in veterinary practice in India.

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Prostaglandins are a group of important cell-signaling molecules involved in the regulation of ovarian maturation, oocyte development, egg laying and associated behaviors in invertebrates. However, the presence of prostaglandin E (PGE), the key enzymes for PGE biosynthesis and its interference by drugs were not investigated previously in the ovary of ticks. The present study was undertaken to assess the modulation of the PGE-mediated pathway in the eclosion blocking effect of flumethrin and terpenoid subfraction isolated from in ticks.

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Amitraz, a member of the formamidine pesticide family, commonly used for ectoparasite control, is applied as a dip or low-pressure hand spray to cattle and swine, and the neck collar on dogs. Data on amitraz were generated mainly on laboratory animals, hens, dogs, and baboons. The data on the toxicity and disposition of amitraz in animals and its residues in the milk are inadequate.

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In the present study, the cytotoxic effects of amitraz, an octopamine receptor agonist on the reproductive system of engorged adult females of Rhipicephalus (Boophilus) annulatus were assessed using histology, electron microscopy and octopamine beta (OCTβ) receptor transcriptional expression analysis. Adult immersion test (AIT) was performed by immersing the fully engorged female ticks for 2 min in different concentrations of amitraz (200, 250, 300, 350 ppm). Amitraz at the dose of 300 ppm, caused an adult tick mortality of 16.

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The present study compares the in vitro efficacy of four chemical acaricides, viz. amitraz, coumaphos, deltamethrin and lindane, against Rhipicephalus (Boophilus) annulatus and Haemaphysalis bispinosa ticks based on adult immersion tests. Amitraz, at 350 ppm, elicited 29.

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Article Synopsis
  • The study investigates the effects of insecticides deltamethrin and amitraz on the reproductive cells of fully engorged female Rhipicephalus (Boophilus) annulatus ticks using ultrastructural analysis.
  • It discovered that untreated ticks' ovaries had oocytes at various developmental stages, characterized by distinct cell membranes and structures, while degenerative changes began five days post-engorgement.
  • Deltamethrin caused more severe damage to oocytes compared to amitraz, leading to changes such as wrinkling, nuclear membrane inconsistencies, and mitochondrial swelling.
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Article Synopsis
  • The study evaluated the acaricidal effects of caffeic acid, nortriptyline, precocene I, and quercetin on the tick species Rhipicephalus annulatus.
  • The adult immersion technique was used to test the compounds at various concentrations for their impact on tick mortality, reproductive index, fecundity, and egg hatching.
  • Results showed that while quercetin had the most significant effect by blocking egg hatching at higher concentrations, overall, the compounds demonstrated very low adult mortality and limited inhibition of fecundity.
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The present communication describes the detailed day wise study of histological changes of the ovary of Rhipicephalus (Boophilus) annulatus in the postengorgement period together with the systematic classification of their oocytes. The ovary of R. (B.

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