Publications by authors named "Kanami Saito"
Article Synopsis
- Clinical trials often leave out elderly patients, leading to limited safety and efficacy data for biologics in this demographic.
- A study comparing elderly (≥65 years) and younger (<65 years) patients using data from the West Japan Psoriasis Registry found that treatment-ending adverse events were more common in the elderly, and malignant neoplasms occurred at higher rates.
- Despite some safety concerns, biologics were effective for both age groups, with no significant differences in treatment outcomes or quality of life indicators between the elderly and younger patients.
A Japanese male in his 30s with no underlying medical condition presented with painless nodules after being bitten by a dog during a stay in Bali, Indonesia, 7 years earlier. He was referred to our department with multiple ulcers, nodules, and masses on the right leg. The final diagnosis was mycetoma caused by Nocardia vulneris, which may have been exacerbated by colonization of Candida parapsilosis and C.
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- * A study analyzed data from 1003 psoriasis patients treated at 20 facilities in Western Japan, focusing on the survival rates of various systemic treatments, including biologics and traditional drugs, from 2010 onward.
- * Recently released interleukin 17 inhibitors had higher survival rates overall, but the differences were less pronounced for patients starting treatment after 2017; factors like obesity and coexisting psoriatic arthritis were linked to worse drug survival rates, while no significant safety concerns were reported
Article Synopsis
- - A study from the West Japan Psoriasis Registry examined 1847 psoriasis patients and found that 10.8% had a family history of the condition, which correlated with an earlier onset and longer duration of the disease.
- - Patients with a family history of psoriasis were more likely to develop psoriatic arthritis (PsA), with a higher percentage (34.7%) compared to those without a family history (26.6%).
- - The research suggests that genetics play a significant role in the development of PsA, indicating that dermatologists should pay closer attention to joint symptoms in patients with psoriasis who have a family history of the disease.
Generalized pustular psoriasis (GPP) is a rare and severe subtype of psoriasis. Because of its rarity, GPP studies with a large sample size have been scarce. We studied the characteristics of GPP and pustular psoriasis using data from the West Japan Psoriasis Registry that had been registered until the end of December 2020.
View Article and Find Full Text PDFPsoriatic arthritis (PsA) is an inflammatory arthritis with as yet unclear pathophysiology. This retrospective, multicenter, cross-sectional study was conducted in 19 facilities in western Japan and aimed to identify patients' characteristics and factors that affect the results of treatment with biologic agents. Of 2116 patients with psoriasis, 285 (13.
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- Drug-induced hypersensitivity syndrome (DIHS) or DRESS is a severe reaction often characterized by skin eruptions and effects on other organ systems, typically linked to certain medications like carbamazepine.
- This report discusses a unique case of DIHS/DRESS triggered by carbamazepine, which presented with acute generalized pustular eruptions and also affected skeletal muscles.
- The findings highlight that while pustular eruptions are uncommon in DIHS/DRESS, they can occur with carbamazepine use, and it’s crucial to consider drug reactions when such symptoms present, even when the skin lesions resemble more typical pustular conditions.