Publications by authors named "Kanako Yoshitsugu"
Article Synopsis
- - Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an effective treatment for diffuse large B-cell lymphoma (DLBCL) due to its graft-versus-lymphoma effect, but identifying which patients will benefit is challenging.
- - Analysis of 1,268 DLBCL patients showed 3-year overall survival and progression-free survival rates at 30.3% and 21.6%, respectively, with various factors impacting patient outcomes post-transplantation.
- - A prognostic index was developed based on four key factors that predict different 3-year progression-free survival rates, aiding in identifying patients who might benefit from allo-HSCT, though its applicability to post-chimeric
Background: Cancer survival is associated with body mass index (BMI). However, the impact of patients' baseline characteristics on allogeneic hematopoietic stem cell transplantation (allo-HSCT) outcomes remains unclear. This study aimed to examine the baseline clinical factors associated with 5-year survival rates in patients undergoing allo-HSCT.
View Article and Find Full Text PDFIntroduction: This study aimed to validate hematopoietic stem cell transplantation (HSCT) treatment via a tailored nutritional pathway in myeloablative conditioning (MAC), determine its efficacy in terms of remission, and explore associations between clinical outcomes and nutritional indicators.
Methods: We included patients who underwent MAC for HSCT at the Shizuoka Cancer Center Stem Cell Transplantation between 2015 and 2019. We evaluated outcomes from the day before treatment initiation (transplant date: day 0) to day 42.
Article Synopsis
- This study explored a nutritional support pathway for patients undergoing hematopoietic stem cell transplantation (HSCT), focusing on pre-conditioning education and oral nutrition to manage nutrition-related issues.
- It compared outcomes between a control group (46 patients) and an enhanced nutrition group (36 patients), measuring factors like body weight loss, skeletal muscle mass loss, and energy expenditure before and after nutritional intervention.
- Results showed that the enhanced nutrition group had better energy intake and weight management, suggesting that this approach could positively influence recovery post-HSCT without increasing gastrointestinal graft versus host disease severity.
Hematopoietic stem cell transplantation carries nutrition-related risks. Therefore, nutritional therapy needs to be initiated before transplantation even takes place. We assessed nutritional risk among patients who underwent allogeneic stem cell transplantation.
View Article and Find Full Text PDFAdult-onset hemophagocytic lymphohistiocytosis (HLH) has features that are distinct from that of HLH in pediatric patients. The clinical records at the Japanese Red Cross Kumamoto Hospital were reviewed. We retrospectively analyzed 34 patients who fulfilled the diagnostic criteria of HLH-2004.
View Article and Find Full Text PDFA 28-year-old man undergoing treatment for hemophagocytic syndrome developed Paecilomyces lilacinus infection in skin ulcers on the face and in the tracheotomy stoma. While his bone marrow was suppressed by chemotherapy with dexamethasone, cyclosporin and etoposide for hemophagocytic syndrome, dental infection led to subacute necrotizing fasciitis caused by Pseudomonas aeruginosa on the right side of the face, resulting in a large area of soft tissue defects. Etoposide was discontinued, and prophylactic treatment with itraconazole was initiated.
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