Publications by authors named "Kanako Kitada-Hamada"
Article Synopsis
- The study investigated the effects of the protein kinase C beta isoform-selective inhibitor LY333531 on pain sensitivity in diabetic rats by examining its impact on specific sensory neurons.
- LY333531 significantly inhibited a sodium current in these neurons, which was found to be heightened in diabetic conditions, indicating an increased excitability associated with diabetes.
- The results suggest that LY333531 may help reduce pain perception in diabetic neuropathy, highlighting its potential as a therapeutic option for alleviating diabetic-induced pain.
