Publications by authors named "Kanakamedala S"

Article Synopsis
  • Triply Periodic Minimal Surfaces (TPMS), specifically Fischer-Koch-S (FKS) scaffolds, show promising properties for bone tissue engineering (BTE) compared to the more commonly used Gyroid scaffolds, particularly in terms of strength and energy absorption.
  • While FKS scaffolds have been previously fabricated in metals and polymers, this study is the first to create them using a ceramic material suitable for BTE, finding that they are 32% stronger and absorb 49% more energy than Gyroid scaffolds with similar porosity.
  • The study suggests that FKS scaffolds could be more effective for applications prioritizing dense bone and strength in BTE, despite a slight decrease in permeability.
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Endometriosis is characterized by the ectopic implantation of a functional uterine lining outside of the uterus. Commonly, it occurs in the fallopian tubes, ovaries, uterosacral ligaments, and gastrointestinal tract. Less commonly, it may occur in the pericardium, pleura, and central nervous system.

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Pancytopenia, a hematologic condition, is a decrease in all three blood cell lines. The two main etiologies include decreased production or increased destruction of cells, as seen in nutritional deficiencies or liver cirrhosis, respectively. Pancytopenia commonly presents with fever, splenomegaly, and lymphadenopathy.

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Uveal melanoma (UM) is an intraocular malignancy with poor survival rates due to the propensity for metastatic spread. Although treatment options exist for localized disease, there are fewer definitive guidelines for metastatic UM. Treatment involves a personalized approach that entails patient-specific aspects, including tumor genetics.

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Introduction: Vascular spinal cord injury following coronary bypass grafting surgery is very rare and this is probably one of few reports of a presumptive partial conus medullaris lesion leading to sudden onset bladder and bowel incontinence which was managed using duloxetine, a selective serotonin and norepinephrine reuptake inhibitor. Duloxetine has been used in selected patients with post-prostatectomy sphincteric incontinence but not, to our knowledge, for spinal vascular lesions.

Case Presentation: A 63-year-old Indian man developed bladder and bowel incontinence immediately following coronary bypass grafting surgery.

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Patients referred to us with "positive" secretin tests and the diagnosis of Zollinger-Ellison syndrome were found to be achlorhydric. This observation led us to study prospectively the accuracy and precision of serum gastrin determinations from commercial laboratories. Synthetic gastrin (G17) was added to serum to achieve gastrin concentrations of 50, 100, 250, 500, 750, 1000, 3000, and 5000 pg/mL after subtraction of the basal value (24 pg/mL).

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Following the curative resection of a pancreatic gastrinoma in a cat, gastrin peptides were purified from the tissue and sequenced. The sequence of cat gastrinoma G17 (18-34) confirms the previously published sequence. The sequence of cat G34 (1-34) is reported for the first time.

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