Publications by authors named "Kanae Yasumatsu"
Article Synopsis
- Maternal immune activation (MIA) due to bacterial infection, specifically through lipopolysaccharide (LPS), can negatively impact fetal brain development and lead to autism spectrum disorder (ASD)-like behaviors in mouse offspring.
- This study shows that LPS exposure triggers an immune response marked by increased IL-17A levels and changes in immune cell activity both in the mother and the fetal brain.
- Blocking IL-17A in the context of LPS-induced MIA helped reduce the ASD-like behaviors in the offspring, highlighting the importance of the IL-17A pathway in this process.
We previously reported that Candida albicans responded to mild heat stress in a range of temperature elevations simulating fever, and concluded that mild heat stress increases susceptibility to antifungal drugs. In this study, we show that mild heat stress causes a morphological change in hyphae during the process of biofilm formation. We found that mild heat stress extended the period of hyphal stage maintenance in C.
View Article and Find Full Text PDFCandida albicans is a human commensal that causes opportunistic infections. Th17 cells provide resistance against mucosal infection with C. albicans; however, the T cell antigens remain little known.
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