Publications by authors named "Kana Tanji"

Article Synopsis
  • * A lung biopsy revealed granulation tissue with necrosis and giant cells, leading to a diagnosis of granulomatosis with polyangiitis (GPA).
  • * Treatment with prednisolone and cyclophosphamide improved his symptoms and reduced PR3-ANCA levels; while rare, GPA can be associated with aortic aneurysms.
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Article Synopsis
  • The study aimed to enhance the management of rheumatoid arthritis (RA) patients by creating a data management system utilizing smart device technology to collect patient information before medical examinations.
  • Fifty-seven RA patients entered their health information through a smart device template, and the system's effectiveness was measured by assessing shorter examination times and comparing self-reported health data with a standard measure (DAS28-ESR).
  • Results showed that the use of smart technology reduced examination duration for most patients and was generally easier to navigate than traditional forms, indicating its potential to improve patient-specific care in RA management.
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Objective The objective of this study was to confirm the efficacy of low-dose mizoribine (MZR), an inhibitor of inosine monophosphate dehydrogenase, as part of synchronized methotrexate (MTX) therapy for rheumatoid arthritis (RA) patients with an inadequate response to various combination therapies of MTX, other synthetic disease-modifying anti-rheumatic drugs (DMARDs) and biological DMARDs. Methods Low-dose MZR was administered to 56 uncontrolled RA patients being treated with MTX and various biological DMARDs. The observation period was 12 months, and the disease activity was evaluated based on the Disease Activity Score in 28 joints (DAS28)-ESR, Simplified Disease Activity Index (SDAI) and serum MMP-3 level.

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A 31-year-old woman with systemic lupus erythematosus and lupus nephritis was treated with prednisone and immunosuppressants. After her lupus nephritis symptoms worsened, both high-dose steroid and cyclophosphamide pulse therapy were administered. The patient developed an intestinal perforation, and laparoscopic Hartmann's surgery was performed on the sigmoid colon.

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