From Mechanisms to Medicine: Neurovascular Coupling in the Diagnosis and Treatment of Cerebrovascular Disorders: A Narrative Review.

Neurovascular coupling (NVC) refers to the process of local changes in cerebral blood flow (CBF) after neuronal activity, which ensures the timely and adequate supply of oxygen, glucose, and substrates to the active regions of the brain. Recent clinical imaging and experimental technology advancements have deepened our understanding of the cellular mechanisms underlying NVC. Pathological conditions such as stroke, subarachnoid hemorrhage, cerebral small vascular disease, and vascular cognitive impairment can disrupt NVC even before clinical symptoms appear.

The Effect of Systemic Inflammatory Response on Mechanical Thrombectomy is Partly Mediated by Pre-thrombectomy Cerebral Edema in Acute Stroke Patients.

Objective: To explore the effect of baseline Systemic Inflammatory Response reflected by platelet-to-lymphocyte ratio (PLR) and pre-thrombectomy cerebral edema reflected by Net Water Uptake (NWU) on futile recanalization in patients with Acute Ischemic Stroke (AIS) after successful thrombectomy, and to investigate the potential mediating role of baseline cerebral edema.

Methods: 134 Patients with anterior circulation ischemic stroke receiving successful thrombectomy were retrospectively studied. Their demographic and clinical characteristics were collected at admission, and the NWU was quantitatively calculated based on baseline computed tomography (CT).

No-reflow phenomenon following stroke recanalization therapy: Clinical assessment advances: A narrative review.

The no-reflow phenomenon (NRP) after successful vascular recanalization in acute ischemic stroke (AIS) has become a major cause of poor clinical prognosis and ineffective recanalization. However, there is currently no clear definition or unified clinical assessment method for the NRP. Therefore, it is urgent to clarify the clinical evaluation criteria for the NRP and develop new no-reflow evaluation techniques so that remedial treatment can be applied to AIS patients suffering from the NRP.

Characterization and Effect of a Nematophagous Fungus sp. nov. for the Biological Control of Corn Cyst Nematode.

The dynamic of plant-parasitic nematode populations in soil is closely related to soil microorganisms. Fungi from cysts were isolated to explore the phenomenon of decline in the population in the soil. Phylogenetic study of partial ITS, , , and gene sequences, in addition to morphological investigations, was utilized to identify a nematode-destroying fungus.

A rare cause of hematochezia: colonic extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALToma): A case report and literature review.

Rationale: Colonic extranodal mucosa-associated lymphoid tissue lymphoma as a cause of hematochezia is rare. Here, we report a case of colonic extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALToma) with presentation of freshy bloody stool and successfully treated by endoscopic mucosal resection.

Patient Concerns: This case was a 69-year-old woman with history of hypertension, reflux esophagitis, and peptic ulcer.

Butyrate supplementation regulates expression of chromosome segregation 1‑like protein to reverse the genetic distortion caused by p53 mutations in colorectal cancer.

The chromosome segregation 1‑like (CSE1L) protein, which regulates cellular mitosis and apoptosis, was previously found to be overexpressed in colorectal cancer (CRC) cells harboring mutations. Therefore, regulating CSE1L expression may confer chemotherapeutic effects against CRC. The gut microflora can regulate gene expression in colonic cells.

Treatment outcomes of patients with stage II pure endometrioid-type endometrial cancer: a Taiwanese Gynecologic Oncology Group (TGOG-2006) retrospective cohort study.

Objective: Choice of hysterectomy and adjuvant treatment for International Federation of Gynecology and Obstetrics (FIGO) 2009 stage II endometrioid endometrial cancer (EEC) is still controversial. Aims of this study were to evaluate survival benefits and adverse effects of different hysterectomies with or without adjuvant radiotherapy (RT), and to identify prognostic factors.

Methods: The patients at 14 member hospitals of the Taiwanese Gynecologic Oncology Group from 1992 to 2013 were retrospectively investigated.

Comparison of vacuum-formed and Hawley retainers: a systematic review.

Introduction: Hawley retainers (HRs) and vacuum-formed retainers (VFRs) are the 2 most commonly used retainers in orthodontics. However, the basis for selection of an appropriate retainer is still a matter of debate among orthodontists. In this systematic review, we evaluated the differences between VFRs and HRs.

[Dynamic experiment on controlling of Microcystis aeruginosa by UV-C irradiation].

A plug-flow UV-C reactor equipped with low pressure UV lamp was utilized to study the suppression effect after UV-C irradiation under the dynamic conditions on Microcystis aeruginosa, a typical cyanobacterium in algae blooms in China. The culture fluid of Microcystis aeruginosa was exposed to UV-C irradiation when pumped through the reactor. After that, the fluid was incubated under the normal culture condition, and sampled at 2 h, 1 d, 3 d, 5 d, 7 d, 9 d for determination of cell density using the inverted system fluorescence microscope.

The effects of sub-lethal UV-C irradiation on growth and cell integrity of cyanobacteria and green algae.

The effects of UV-C irradiation on algal growth and cell integrity were investigated to develop a potential method for preventing cyanobacterial blooms. The toxic cyanobacterium Microcystis aeruginosa and three common freshwater green algae Chlorella ellipsoidea, Chlorella vulgaris, and Scenedesmus quadricanda were exposed to UV-C irradiation at 0-200mJcm(-2) and subsequently incubated for 9-15 d under normal culture conditions. Cell density and cell integrity were assessed using flow cytometry.