Publications by authors named "Kan Cui"

Article Synopsis
  • Histone post-translational modifications are key in regulating gene expression and biological processes, but their impact on fungal virulence is not well understood.!
  • This study focused on a specific histone methyltransferase, which was found to be important in maintaining fungal virulence and affecting mycotoxin production.!
  • The findings suggest that the absence of this methyltransferase leads to reduced virulence and impaired responses to environmental stresses in the fungal strains studied.!
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is a devastating fungal pathogen that causes severe crop losses worldwide. It is of vital importance to understand its pathogenic mechanism for disease control. Through a forward genetic screen combined with next-generation sequencing, a putative protein kinase, Cak1, was found to be involved in the growth and pathogenicity of .

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Replication factor C (RFC) is a heteropentameric ATPase associated with the diverse cellular activities (AAA+ATPase) protein complex, which is composed of one large subunit, known as RFC1, and four small subunits, RFC2/3/4/5. Among them, RFC1 and RFC3 were previously reported to mediate genomic stability and resistance to pathogens in . Here, we generated a viable () mutant with a single amino acid substitution by site-directed mutagenesis.

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