[Choice of surgical correction of urodynamics in ureteral tuberculosis].

To determine an optimal choice of surgical correction of urodynamic disorders and time of its conduction in ureteral tuberculosis, we made a retrospective analysis of 271 case histories of primary patients with tuberculosis of the kidneys who had x-ray picture of ureteral lesions, hydro- or ureterohydronephrosis. We used the following methods of this correction: calycoureteroanastomosis (n = 7, 2.5%), plastic reconstruction of the pelvoureteral segment (n = 9, 3.

[Capacities of rapid diagnostic methods in renal tuberculosis].

The paper comparatively assesses routine and new medical technologies (metachromatic urine test, polymerase chain reaction, chromatographic mass spectrometry, and enzyme immunoassay) for detection of Mycobacterium tuberculosis and tuberculosis antibodies. It is shown that molecular biological and immune assays may be used only for rapid diagnosis and screening, followed by a full-scale phthisiourological study as the detection of markers of Mycobacterium tuberculosis and tuberculosis antibodies cannot be a criterion for establishing renal tuberculosis. The authors consider that the conventional microbiological tests whose validity is beyond question in case of positive results are the most established and practice-tested canons of phthisiourological diagnosis.

[Current methods in diagnosis of the kidney tuberculosis].

Conventional and updated medical technologies of detecting M. tuberculosis (MT) and tuberculosis antibodies (TAB) were compared. It is shown that molecular-biological and immunological methods can be used only in rapid diagnosis and screening.

[Treatment of renal tuberculosis].

Three groups of parameters of 4 tuberculostatics effects on tuberculosis of the kidneys and general condition were singled out basing on comparative efficacy of 3 and 4 mycobacterial drugs: more effective, equally effective and negative. Higher efficacy manifested with greater number of cases of leukocyturia elimination and conversion of cultivable mycobacteria into uncultivable ones, more obvious morphological signs of tuberculous inflammation involution. Equal efficacy of 3 and 4 drugs was characterized by the same rate of mycobacteriuria continuation and detection of mycobacteria in caverns from the removed tuberculous kidney.

[Comparative evaluation of therapeutic effects of 3 and 4 antitubercular agents at the initial stage of the treatment of renal tuberculosis].

Three groups of the parameters of the therapeutic effects of 3 and 4 antituberculous drugs on renal tuberculous inflammation were identified. The primary effect of 4 drugs was much frequently manifested itself by the normalization of urinalysis and the transfer of cultured to uncultured Mycobacterium tuberculosis (MBT). The equivalent effect of 3 and 4 drugs was characterized by the similar rate of continuation of specific mycobacteriuria, by the detection of MBT in the cavernous contents from the removed tuberculosis-afflicted kidney and by the equivalent morphological characteristics of tuberculous inflammation involution.

[Role of polymerase chain reaction in diagnosing tuberculosis of the bladder and male sex organs].

Detection of M. tuberculosis DNA by polymerase chain reaction (PCR) and standard technique was compared in 76 new cases of urogenital tuberculosis. In the urinary test PCR confirmed tuberculous etiology of the disease and corresponded to M.

[Regeneration of post-tuberculous bladder after intestinal plastic surgery].

The effects of regeneration of the urinary bladder on the intestinal transplant were assessed in conducting detrusor resection after creation of an artificial reservoir for urine in 107 patients with posttuberculous microcystis. It was found that the condition of the intestinal transplant depended on severity of anatomic changes and the scope of detrusor resection. The best results of creation of a new artificial reservoir for urine are achieved if the bladder, as a cause of regenerative process and unfavourable factor for operation outcome is totally removed.

[Urinary bladder cancer in patients with tuberculous and post-tuberculous cystitis].

125 patients with tuberculous and posttuberculous cystitis were examined using cytological test of the aspirate from the bladder for atypical cells and histological investigation of the biopsy. Cancer of the bladder has developed in long-term chronic tuberculous or posttuberculous cystitis in 4% of the cases. The best objective method of the diagnosis was histological examination of the biopsy obtained from cancer-suspected sites of the bladder mucosa.

[Urogenital tuberculosis in the Ukraine population].

The prevalence and incidence rates of urogenital tuberculosis in the Ukraine in the past 10 years were studied. They tended to decrease in the first period (1988-1992) and to become stable in the second period (1993-1997), being equal to 10.71 and 1.

[Intravascular laser radiation of blood in the multimodality treatment of patients with urogenital tuberculosis].

Laser therapy was performed in 45 patients with tuberculosis of the urinary system and male genitals. The radiation was found to have a positive action on the patients' general condition and short-term immunomodulating effect. Following a month, immunological parameters became baseline or near-baseline.

[The ultrasonic diagnosis of renal tuberculosis].

Informative value of ultrasonography potential in the diagnosis of nephrotuberculosis was studied by comparison with conventional x-ray and intraoperative findings in 78 relevant patients. Three patterns of renal ultrasonic architectonics changes in nephrotuberculosis were revealed: 1) focal heterogeneity of renal parenchyma, 2) pseudocystic type, 3) hydronephrotic transformation. It is concluded that ultrasonography is superior to routine diagnostic methods, but is recommended for use in combination with standard methods of phthisiourological diagnosis.

[The chemotherapy of patients with prostatic tuberculosis].

The authors examined the efficacy of various chemotherapeutic regimes in the management of patients with tuberculosis of the prostate. The data of bacteriostatic secretion activity of the prostate showed that the most effective regimes were as follows: 1) isoniazid and ethambutol followed by galvanization of the prostatic region, then rifampicin suppository containing dimexid; 2) isoniazid and rifampicin suppository containing dimexid; oral ethambutol. Proper curative measures depending on the clinicomorphological types of the tuberculous prostate and their duration are also given.

[Surgical treatment of microbladder of tuberculous etiology].

In tuberculous microcysts two technics of plastic surgery are suggested depending on the state of the prostatic gland and urethra. In patients with microcysts without specific lesions of the prostatic gland and urethra vertical sigmocystoplasty was performed after subtotal resection of the urinary bladder. In microcysts associated with tuberculosis of the prostatic gland or urethra perineal sigmocystoplasty after the authors' technic was employed.