Production assessment of non-carrier-added Au by (n,γ) reaction.

Gold-199 is a promising theranostic radionuclide for targeted radioimmunotherapy as well as for scintigraphy and dosimetry. Au can be produced in two methods in the direct and indirect routes of the reactor production via Au(n,γ)Au(n,γ)Au as the direct or Pt(n,γ)Pt→Au as the indirect method. This investigation described the development of a method for the reactor production of no-carrier-added (NCA) Au through neutron activation of natural Pt in Tehran Research Reactor (TRR) at a thermal neutron flux of 3.

Investigations of proton and deuteron induced nuclear reactions on natural and enriched Titanium, Calcium and Vanadium targets, with special reference to the production of Sc.

Sc could be used in SPECT imaging and also suitable for targeted therapy of small tumors. The excitation functions for the production of Sc and accompanying impurities via proton and deuteron bombardment of Calcium, Titanium and Vanadium targets were evaluated by three nuclear codes, ALICE, TALYS and EMPIRE. Therefrom, integral yields of Sc and also Sc as a main impurity were calculated.

Investigation of the thermal performance of Cu target for Zn production.

The flow rate of coolant and the particle beam current are important when high beam current irradiations are intended for production of radionuclides. The beam current on Cu target to produce Zn via the Cu(p,n)Zn reaction was investigated and the beam current was obtained more than 350 μA that is the maximum allowed beam current used for producing medical radioisotopes in Nuclear Science and Technology Research Institute of Iran. In addition, the temperature distribution on the target under the different cooling water flow rates has been simulated based on finite element analysis program.

Computational simulation of UO, ThO and UO-Al pills to estimate (p,fission) Mo yield in the modeled targets irradiated by CYCLONE30 accelerator.

Mo is important for both therapy and imaging purposes. Accelerator and reactor-based procedures are applied to produce it. Newly proton-fission method has been taken in attention by some research centers.

Assessment of the direct cyclotron production of (99m)Tc: An approach to crisis management of (99m)Tc shortage.

Nowadays, the cyclotron production of technetium-99m ((99m)Tc) has been increased, due to the worldwide (99m)Tc generator shortage. In the present work, an improved strategy for the production of (99m)Tc, using the proton irradiation of the enriched (100)Mo was developed. The performance of this method in terms of the production yield, chemical purity, radiochemical purity, as well as radionuclide purity was evaluated.