Publications by authors named "Kamran Aghaie"
Article Synopsis
- A study was conducted to evaluate how gastroenterologists manage Barrett's esophagus (BE) through a survey sent to various practitioners across the U.S.
- The survey, which had a 45% response rate, revealed that most respondents were experienced gastroenterologists working in community settings, with many not using established classification systems like the Prague C & M.
- Findings indicated varied approaches to treatment: 86% monitored nondysplastic BE with surveillance, while treatment strategies for high-grade dysplasia included referrals to specialized centers and endoscopic ablation practices.
Objective: This study investigated the effects of ginsenoside Rb1 (Rb1) on injury-induced intimal hyperplasia in ApoE knock out (ApoE -/-) mice. We also examined the value of an ultrasound micro-image system in dynamic monitoring of lumen diameter and flow velocity.
Methods: After guide wire injury of the distal left common carotid artery (CCA), ApoE-/- mice were treated with intraperitoneal infusion of normal saline (NS), homocysteine (Hcy), ginsenoside Rb1 (Rb1), or Hcy+Rb1 for 4 wk.
Background: Clinical data have shown that an increased level of serum soluble CD40 ligand (sCD40L) is associated with atherosclerogenesis. We hypothesize that sCD40L induces proliferation and migration of vascular smooth muscle cells (VSMCs) through activation of matrix metalloproteinases (MMPs).
Methods: Human VSMCs were treated with sCD40L (1 or 5 microg/mL).