Effect of Beta-Blocker on Long-Term Major Cardiovascular Events in High Atherosclerotic Risk Population.

Purpose: Beta-blocker is a frequently used medication in cardiovascular diseases. However, long-term benefit of beta-blocker in patients with preserved left ventricular ejection function (LVEF) on major adverse cardiovascular events (MACEs) is uncertain.

Methods: The Cohort Of patients with high Risk for cardiovascular Events (CORE-Thailand) was a prospective study that enrolled Thai patients with high atherosclerotic risk including multiple atherosclerotic risk factors and established atherosclerotic cardiovascular diseases.

Increased small extracellular vesicle levels and decreased miR-126 levels associated with atrial fibrillation and coexisting diabetes mellitus.

Background: Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia. Diabetes mellitus (DM) is one of the risk factors for the development of stroke and thromboembolism in patients with AF. Early identification may reduce the incidence of complications and mortality in AF patients.

Increased expression of six-large extracellular vesicle-derived miRNAs signature for nonvalvular atrial fibrillation.

Backgrounds: Non-valvular atrial fibrillation (AF) is the most common type of cardiac arrhythmia. AF is caused by electrophysiological abnormalities and alteration of atrial tissues, which leads to the generation of abnormal electrical impulses. Extracellular vesicles (EVs) are membrane-bound vesicles released by all cell types.

Neck circumference as a predictor of metabolic syndrome: A cross-sectional study.

Background: Data relating to the association between neck circumference (NC) and metabolic syndrome (MetS) in Southeast Asian population are scarce.

Aims: We aimed to investigate association between NC and MetS in Thai adults, and to determine gender-specific NC cutoff values for predicting MetS.

Methods: This cross-sectional study enrolled patients aged ≥18years that attended the health examination center at Siriraj Hospital (Bangkok, Thailand) during February 2016 to January 2017.

Effect of Breast Sling Use on Transthoracic Echocardiographic Examination Time and Image Quality in Women with Large Breasts.

Background: Transthoracic echocardiographic examinations in women with large breasts are technically demanding and can lead to suboptimal image quality, excessive scan time, and cause pain and discomfort to patients.

Objective: Evaluate the effects of self-made breast sling used during transthoracic echocardiographic examination on scanning time, image quality, pain, and satisfaction in women with large breasts.

Material And Method: A self-made breast sling was developed by the study team and tested in 26 women with bra cup size of C or larger, who were scheduled for transthoracic echocardiography.

Certain hormonal markers in urban Thai adults with metabolic syndrome.

Background: The prevalence of metabolic syndrome (MS) accompanied with cardiometabolic complications has progressively increased in Thailand. The roles of insulin resistance, leptin, adiponectin, and free testosterone as prognostic indicators of MS among Thai population were evaluated

Material And Method: Men and women aged 34 to 89 years (n = 308) having 0-5 criteria of MS according to NCEP III with Asian-specific cut-points for waist circumference were enrolled in this cross-sectional study. Blood glucose, lipids, insulin, leptin, adiponectin, and free testosterone were measured

Results: Each component of MS, especially the enlarged waist, adversely affected insulin sensitivity.

Abnormal liver enzymes in Thai patients with metabolic syndromes.

Objective: Elevated transaminases have been found to be associated with metabolic syndrome (MS) in many populations but little is known in Asians. The present study aimed to investigate the association between elevated hepatic enzymes in Thai patients diagnosed with MS.

Material And Method: A cross-sectional study on 2,585 Thais was conducted.

Dobutamine stress echocardiography for the evaluation of coronary artery disease in Thai population: Siriraj experience.

Objective: No previous report of dobutamine stress echocardiography in the Thai population has been available. The present study seeks to document the protocol, indications, results and safety of dobutamine stress echocardiography performed at Siriraj Hospital.

Material And Method: The authors studied 421 [mean age 67.

Effectiveness of amiodarone for conversion of atrial fibrillation to sinus rhythm: a meta-analysis.

Background: Although clinicians sometimes choose amiodarone to convert atrial fibrillation (AF) to sinus rhythm, no current and comprehensive systematic review has summarized its effectiveness.

Objective: To review the effectiveness of amiodarone in converting AF to sinus rhythm over a 4-week period.

Methods: Two reviewers conducted a systematic search for randomized trials in databases, complemented by hand searches and contact with experts.