Preparation, Characterization and Adsorption Potential of Grainy Halloysite-CNT Composites for Anthracene Removal from Aqueous Solution.

Grainy Hal-CNT composites were prepared from powder halloysite nanoclay (Hal) and carbon nanotubes (CNTs). The effect of the amount and type of CNTs, as well as calcination temperature on morphology and properties of Hal-CNT composites and their adsorption capacity of anthracene (ANT), were studied. The surface topography of granules was heterogenous, with cracks and channels created during granulation of powder clay and CNTs.

Kinetics and equilibrium of the sorption of bisphenol A by carbon nanotubes from wastewater.

The aim of this study was to determine the sorption potential of carbon nanotubes (CNTs) to bisphenol A (BPA) contained in synthetic wastewater whose composition corresponds to biologically treated effluents. These nanotubes differed in their outer diameter, the number of graphene layers and the presence of modifying functional groups. Based on the nitrogen adsorption-desorption isotherms, mensuration of the specific surface area and pore size distribution was undertaken.

[The influence of selected prognostic factors on the results of combined treatment of invasive carcinoma of the cervix on stage IB and stage IIA].

This is a retrospective analysis of 180 patients treated by combination of radical surgery and radiotherapy for invasive carcinoma of the cervix in stage IB and IIA. The influence of the following prognostic factors on the survival has been evaluated: the presence of pelvic lymph node metastases, histopathology of the tumor, the size of the primary tumor, presence of vascular space invasion and surgical margines. Nodal status has proved to be the most important prognostic factor: 91% of patients without pelvic lymph node metastases survived 5 years, 57% with up to two metastases and 36% with three and more metastases to the pelvic nodes.

[Carcinoma of the fallopian tube. Clinical analysis of 40 cases].

The results of clinical analysis of 40 cases of primary carcinoma of the fallopian tube are presented. All patients were treated with surgery and post operative external beam irradiation. Overall 5 years survival was 37% and symptom free survival 21%.

Spontaneous corneal neovascularization in nude mice. Local imbalance between angiogenic and anti-angiogenic factors.

Purpose: The present study considered the hypothesis that spontaneous neovascularization of the cornea of nude mice results from a local imbalance between angiogenic and anti-angiogenic factors.

Methods: The presence of angiogenic and anti-angiogenic factors was revealed by exchanging orthotopic corneal allografts between nude BALB/c mice and normal (hirsute) euthymic BALB/c mice and observing the presence, intensity, and degree of corneal neovascularization before and after grafting.

Results: Avascular corneal grafts from normal BALB/c donors resisted neovascularization after grafting to spontaneously vascularized graft beds in nude mice.

Selective up-regulation of D-1 dopamine receptors following chronic administration of SCH 39166 in primates.

Caudate, putamen and frontal cortex tissues were obtained from rhesus monkeys that had taken part in a toxicology study required by the Food and Drug Administration. These monkeys had received daily oral treatments of SCH 39166 at three different doses (3, 12 and 48 mg/kg) for three consecutive months. Plasma membranes from the caudate and putamen were analyzed for changes in D-1 and D-2 receptor affinity and number using saturation analyses of 3H-SCH 23390 and 3H-spiperone binding, respectively.

Neuropeptide degradation by large vessel and microvessel-derived endothelial cells in vitro: cell surface catabolism of thyrotropin releasing hormone (TRH).

Cell surface ectopeptidase activity of purified, cultured large vessel and microvessel-derived endothelial cells (EC) was studied. Degradation of thyrotropin releasing hormone (TRH), and production of cyclo-His-Pro was significantly increased (P less than 0.001) in large vessel EC compared with microcapillary EC.

Cultured brain endothelium inhibits the cytocidal action of natural killer cells on glioma.

The killing of GL26 and YAC-1 cells by natural killer cells (NKC) is reduced in the presence of a monolayer of endothelial cells. This reduction in cytotoxicity correlates with the degree of adhesion between the tumor cells and the endothelial monolayers. The cytotoxicity of NKC toward glioma was 10% when carried out on plastic, but a monolayer of endothelium derived from brain inhibited the cytotoxicity by about 90%.

Preclinical safety evaluation of the benzodiazepine quazepam.

7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-2H-1,4- benzodiazepine-2-thione (quazepam, Sch 16134, Dormalin) was evaluated for evidence of systemic toxicity, carcinogenicity and reproductive toxicity in several laboratory animal species including the hamster. Mutagenic potential was also assessed in one in vivo and three in vitro assays. In some studies, diazepam was used as a comparative control.

Specificity of adhesion between murine tumor cells and capillary endothelium: an in vitro correlate of preferential metastasis in vivo.

We have compared the rate and extent of adhesion of various types of mouse tumor cells to endothelial cells derived from different organ sources. Our panel of tumors has included sarcoma, bladder carcinoma, glioma, teratoma, hepatoma, endothelioma, mammary adenocarcinoma, and lymphoma cells. Endothelial cell monolayers have included murine microvascular endothelial cells from ovary, brain, lung, and liver as well as large vessel endothelium from thoracic duct and dorsal aorta.

Heterogeneity of mouse vascular endothelium. In vitro studies of lymphatic, large blood vessel and microvascular endothelial cells.

Microvascular endothelial cell cultures have been established from mouse lung, liver, brain, heart, placenta, kidney, urinary bladder, mammary gland, ovary and epididymal fat pad. In addition, large vessel endothelial cells have been obtained from the mouse aorta and thoracic duct. The heterogeneity of these cells has been shown by flow cytometric determination of angiotensin-converting enzyme, by differential presence of the acetyl low density lipoprotein receptor, by the variable expression of cell surface antigens, and by differential binding of various plant lectins.

Inhibition of tumour-induced angiogenesis by systemically administered protamine sulphate.

Systemic administration of protamine sulphate significantly decreased the intensity of angiogenesis induced in X-ray immunosuppressed (BALB/c X DBA/2W) F1 mice by either HEp-2 (human larynx carcinoma) cells or semi-syngeneic splenocytes injected intradermally. In vitro experiments have shown that protamine sulphate markedly decreases the proliferation of human endothelial cells as assessed by 3H-TdR incorporation assay. In contrast, the proliferation of HEp-2 cells was not affected, and only slight inhibition of normal human fibroblasts could be demonstrated.

Protease-mediated enhancement of lymphocyte-induced angiogenesis in X-ray irradiated mice.

Angiogenesis was induced in mice by intradermal injection of semi-syngeneic splenocytes, and after three days the number of newly formed blood vessels at the injection site was counted. When recipients were total-body irradiated with 700 R 2 hours before the lymphocyte injection, the angiogenesis was significantly higher than in non-irradiated mice. The angiogenesis enhancement was of a systemic (not local) character as revealed in experiments with shielding of irradiated animals.

Human peripheral blood T lymphocyte subpopulations isolated on the basis of their affinity for sheep red blood cells differ in angiogenesis-inducing capability.

Human peripheral blood lymphocytes injected intradermally into X-ray immunosuppressed mice were tested for angiogenesis-inducing capacity. Both T and B lymphocytes evoked angiogenesis of the same intensity. The total T cell population was fractionated into three subpopulations on the basis of their different affinities for sheep red blood cells (SRBC).

Grafting of isolated allogeneic keratocytes in the treatment of experimental defects in the rabbit cornea.

Keratocytes isolated by enzymatic digestion from the rabbit cornea propria were suspended in rabbit plasma clot and then transplanted into deep, experimental defects of the allogeneic recipients cornea. This procedure resulted in improved healing and transparency of the cornea observed up to two years after operation.

Heterotopic transplantation of syngeneic lymphoid tissues in mice. The ability of graft repopulation cells to enhance cell-mediated immunity as measured in the lymphocyte-induced angiogenesis assay.

Fragments of murine spleen and Peyer's patches were transplanted under the kidney capsule of syngeneic recipients. The ability of graft-repopulating cells to enhance cell-mediated immunity was tested in a lymphocyte-induced angiogenesis assay. The ability to evoke angiogenesis expressed by cells isolated from 10-day-old grafts of both tissues was significantly lower than that of cells isolated from organs in situ and was restored to control levels in both types of grafts 30 days after transplantation.