Publications by authors named "Kamila Melnikov"
Article Synopsis
- Caenorhabditis elegans is being explored as a tool for chemotaxis testing due to its sensitive olfactory system, especially in cancer diagnostics.
- This study aimed to assess the nematode's ability to differentiate between urine samples from healthy individuals and those with breast or colon cancer.
- Results indicated a significant difference in the nematodes' responses, with high diagnostic sensitivity (96% for breast cancer, 100% for colon cancer) and moderate specificity (62%) in detecting cancer through urinary volatile organic compounds.
represents a favorite non-mammalian animal model, which is often used to study the effect of foreign substances on living organisms. Its epidermal barrier is a primary biological barrier that protects nematodes from the toxicity of chemicals. In this study, we investigated the effect of Bisphenol A (BPA), an endocrine disrupting chemical, and its structural analog Bisphenol S (BPS), which is often used as a substitute for BPA in some products, on the behavior of wild type (N2) and mutant strain, which is characterized by the production of abnormal cuticle blisters.
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