Publications by authors named "Kamila Chraibi"
Article Synopsis
- Group B streptococcus (GBS) is a key cause of neonatal sepsis, primarily activating TLR2, with the specific components responsible still unclear.
- Research revealed that the lipoproteins, rather than lipoteichoic acid (LTA), play a critical role in TLR2 activation in GBS, as mutations preventing lipoprotein maturation led to reduced cytokine induction.
- The study concluded that mature bacterial lipoproteins are the main factors responsible for TLR2 activation and significantly impact the severity of GBS-related sepsis.
