Vanillin and IGF1-loaded dual-layer multifunctional wound dressing with micro-nanofibrous structure for full-thickness wound healing acceleration.

Multifunctional dual-layer wound dressings hold significant promise for comprehensive full-thickness wound management by closely mimicking the native skin structure and features. Herein, we employed an innovative approach utilizing electrospinning techniques to develop a dual-layer dressing comprising a microfibrous Ecoflex®-Vanillin (Ex-Vnil) top layer (TL) and a nanofibrous Soluplus®-Insulin-like growth factor-1 (Sol-IGF1) bottom layer (BL). The tensile properties of dual-layer wound dressings were within the standard range for use in skin tissue regeneration.

Evaluation of serum levels of irisin, tumor necrosis factor and some biochemical variables in males with prostate cancer in Baghdad City.

Prostate cancer is the most common type after the age of fifty. It affects males and affects the prostate gland, which protects the function of sperm by producing semen. The current study was designed to evaluate prostate cancer infection effects on some biomarkers such as irisin, Tumor necrosis factor-TNF-α, prostate acid phosphates -PAP, Glutathione-GSH, malondialdehyde-MDA, urea, and creatinine.

Enhancing tribological performance of electric vehicle lubricants: Nanoparticle-enriched palm oil biolubricants for wear resistance.

The transition to electric vehicles (EVs) calls for sustainable advancements in automotive lubricants, as traditional fossil-fuel-based products pose environmental challenges. Palm oil-based biolubricants enriched with nanoparticles present a promising eco-friendly alternative that meets the thermal and tribological demands of EVs. This paper aims to analyze the development of nanoparticle-enriched palm oil-based biolubricants, aimed at improving the sustainability and performance of electric vehicle (EV) lubrication systems.

Metabolomics reveals a differential attitude in phytochemical profile of black tea ( Var. ) during processing.

Black tea's quality and flavor are largely influenced by its processing stages, which affect its volatile and non-volatile phytochemicals. This study aimed to optimized black tea manufacturing by investigating withering time, fermentation time, and temperature's impact on sensory quality. Using a U* (15) uniform design, optimal conditions were determined: 14 h of withering, 5.

Vasculo-osteogenic keratin-based nanofibers containing merwinite nanoparticles and sildenafil for bone tissue regeneration.

Vascularization of bone tissue constructs plays a pivotal role in facilitating nutrient transport and metabolic waste removal during the processes of osteogenesis and bone regeneration in vivo. In this study, a sildenafil (Sil)-loaded nanofibrous scaffold of keratin/Soluplus/merwinite (KS.Me.

Meta-Analysis of Interobserver Agreement in Assessment of Interstitial Lung Disease Using High-Resolution CT.

Background High-resolution CT (HRCT) is central to the assessment of interstitial lung disease (ILD), and accurate classification of disease has important implications for patients. Evaluation of imaging features can be challenging, even for experienced thoracic radiologists. Previous work has provided equivocal evidence on the interpretation of HRCT features at ILD-related imaging.

Drug-induced ER stress leads to induction of programmed cell death pathways of the malaria parasite.

The rapid emergence of drug resistance against the mainstream antimalarial drugs has increased the need for development of novel drugs. Recent approaches have embarked on the repurposing of existing drugs to induce cell death via programmed cell death pathways. However, little is known about the ER stress response and programmed cell death pathways of the malaria parasite.

A case of prosthetic joint infection due to the rare opportunist yeast, .

Background And Purpose: Invasive fungal infections caused by () have recently increased despite the low virulence potential of this yeast. However, limited information about the widely-used commercial biochemical identification systems has led to an underestimation of infections in clinical settings.

Case Report: This study reports a case of prosthetic joint infection in a patient who had a previous history of total knee replacement surgery.

Unlocking Nature's Potential: A Comparative Study of Bioactive Compounds Extracted from Tropical Microalgae.

To promote the use of marine microalgae for nutraceuticals, we aimed to characterize extracts of Nannochloropsis oculata, Porphyridium cruentum, and Skeletonema costatum, all of which harbor numerous bioactive substances. Chlorophylls and carotenoids were identified as the primary pigments in N. oculata and S.

Endoplasmic reticulum localized TMEM33 domain-containing protein is crucial for all life cycle stages of the malaria parasite.

Endoplasmic reticulum (ER) plays a pivotal role in the regulation of stress responses in multiple eukaryotic cells. However, little is known about the effector mechanisms that regulate stress responses in ER of the malaria parasite. Herein, we aimed to identify the importance of a transmembrane protein 33 (TMEM33)-domain-containing protein in life cycle of the rodent malaria parasite Plasmodium berghei.

A novel designed nanofibrous mat based on hydroxypropyl methyl cellulose incorporating mango peel extract for potential use in wound care system.

Skin tissue is damaged by factors such as burns, physical injuries and diseases namely diabetes. Infection and non-healing of burn wounds and lack of angiogenesis in diabetic wounds lead to extensive injuries and death. Therefore, the design of wound dressings with antibacterial and restorative capabilities is very important.

Evaluating the performance of artificial intelligence software for lung nodule detection on chest radiographs in a retrospective real-world UK population.

Objectives: Early identification of lung cancer on chest radiographs improves patient outcomes. Artificial intelligence (AI) tools may increase diagnostic accuracy and streamline this pathway. This study evaluated the performance of commercially available AI-based software trained to identify cancerous lung nodules on chest radiographs.

The effect of κ-carrageenan and ursolic acid on the physicochemical properties of the electrospun nanofibrous mat for biomedical application.

Wound dressing materials such as nanofiber (NF) mats have gained a lot of attention in recent years owing to their wonderful effect on accelerating the healing process and protection of wounds. In this regard, three different types of NF mats were fabricated using pure polyvinylpyrrolidone (PVP), PVP/κ-carrageenan (KG), and ursolic acid (UA) in the optimal PVP/KG ratio by electrospinning method to apply them as wound dressings. The morphology, chemical structure, degradation, porosity, mechanical properties and antioxidant activity of the produced NFs were investigated.

Role of Resistin in Various Diseases with Special Emphasis on Periodontal and Periapical Inflammation - A Review.

Resistin is a small adipocyte-specific secretory hormone molecule. It has been associated with a number of cellular and metabolic processes. It has also been essentially implicated to have a vital role in the interplay between insulin resistance, obesity, and type II diabetes.

Dermatologists' Perceptions of the Use of Teledermatology in Managing Hidradenitis Suppurativa: Survey Study.

Background: The field of teledermatology has expanded tremendously and has been used for conditions including hidradenitis suppurativa (HS). However, due to the sensitive location of lesions, HS may be considered less suitable for teledermatology.

Objective: We sought to assess dermatologists' experiences and perceptions toward using teledermatology for HS relative to atopic dermatitis (AD) as a comparison.

^{138}Ba(d,α) Study of States in ^{136}Cs: Implications for New Physics Searches with Xenon Detectors.

We used the ^{138}Ba(d,α) reaction to carry out an in-depth study of states in ^{136}Cs, up to around 2.5 MeV. In this Letter, we place emphasis on hitherto unobserved states below the first 1^{+} level, which are important in the context of solar neutrino and fermionic dark matter (FDM) detection in large-scale xenon-based experiments.

Wisepatern mastopexy for natural breast ptosis symmetrization after giant lipoma excision: Case report.

Introduction And Importance: Giant breast lipoma is an uncommon benign tumor that develops in the breast parenchyma. Wisepatern technique involves lifting the skin in both vertical and horizontal directions to raise and reshape the breasts into a less ptotic shape.

Case Presentation: A 40-year-old woman came to the Surgical Oncology Polyclinic with the breast size is asymmetric, the right is 4× larger than the left.

Our experience in one-step closure of patients with facial clefts in Surakarta: Serial cases at Dr. Moewardi Hospital.

Introduction And Importance: Facial cleft is a morphological disruption or defect of facial structure, a rare and challenging craniofacial malformation. The treatment of rare facial cleft is complex, and evaluating its long-term outcome is challenging because of its low incidence.

Case Presentation: In case one, a five-month-old boy presented with unilateral facial cleft Tessier 3.

Online attendance system based on facial recognition with face mask detection.

This paper presents an online system for recording attendance based on facial recognition incorporating facial mask detection. The main objective of this project is to develop an effective attendance system based on face recognition and face mask detection, and to provide this service online through a browser interface. This would allow any user to use this system without the need to install special software.

Knowledge, Attitudes, and Practices of Dental Healthcare Workers toward Hepatitis B Virus in Khartoum/Sudan.

Objective: The aim of the present study is to evaluate dental healthcare workers' knowledge, attitudes, and practices toward hepatitis B infection.

Materials And Methods: This study was a cross-sectional self-administered, structured questionnaire survey that was conducted in Khartoum/Sudan. The questionnaire was completed by 177 dental healthcare providers who practice in public dental clinics in Khartoum state.

Comparative Assessment of the Effect of Three Various Local Drug Delivery Medicaments in the Management of Chronic Periodontitis.

Aim: The aim of this study was to evaluate the efficacy of three different local drug delivery medications in the treatment of chronic periodontitis.

Materials And Methods: Sixty participants, aged 30-55 years, were involved in the current research. Participants who fulfilled the inclusion criteria entered the study and were allocated at random to one of the three groups, each comprising 20 patients as: group A: Scaling and root planing (SRP) with local application of doxycycline gel, group B: SRP with local application of tetracycline fibers, and group C: SRP with local application of chlorhexidine gel.