Publications by authors named "Kamel Hamami"
Article Synopsis
- The study investigates the effectiveness of different treatment combinations, particularly ceftazidime/avibactam, against OXA-48-producing E. coli infections in an osteomyelitis model using rabbits.
- Researchers induced osteomyelitis in rabbits and evaluated various treatment regimens, finding that combinations of ceftazidime/avibactam with other antibiotics significantly reduced bacterial density in bones compared to controls.
- The results suggest that ceftazidime/avibactam, especially when combined with colistin, fosfomycin, or gentamicin, could be an effective treatment strategy for managing OXA-48/ESBL-producing E. coli infections without leading to resistance development.
Urinary tract infections (UTIs) are the most common bacterial infections in patients with neurogenic lower urinary tract dysfunction. Antibiotic options for prophylaxis or curative treatment in case of recurrent UTIs, especially due to multidrug-resistant organisms (MDRO), are scarce. We present the case of a 72-year-old man with neurogenic lower urinary tract dysfunction and history of frequent recurrent UTIs due to multiple MDROs who was successfully treated with hyaluronic acid (HA) and chondroitin sulfate (CS) bladder instillations.
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