A review of recent progress in alginate-based nanocomposite materials for tissue engineering applications.

Integrating nanotechnology with tissue engineering has revolutionized biomedical sciences, enabling the development of advanced therapeutic strategies. Tissue engineering applications widely utilize alginate due to its biocompatibility, mild gelation conditions, and ease of modification. Combining different nanomaterials with alginate matrices enhances the resulting nanocomposites' physicochemical properties, such as mechanical, electrical, and biological properties, as well as their surface area-to-volume ratio, offering significant potential for tissue engineering applications.

Effects of Varying Light Durations on Sperm Quality in Rams.

This investigation aimed to study the effects of varying light exposure durations on ram sperm. A total of 25 rams were randomly divided into five groups. The control group was exposed to light durations of 12 h, while the experimental groups were exposed to light durations of 14, 16, 18, and 20 h.

Predictors of renal outcomes and mortality in patients with renal vein thrombosis: a retrospective multicenter study.

Background: Studies on renal vein thrombosis have been conducted as case reports or case series. The renal outcomes and mortality risk of renal vein thrombosis have not been fully established. We aimed to investigate the clinical characteristics, treatment modalities, and predictors of renal outcomes and mortality in patients with renal vein thrombosis in a large multicenter cohort.

Expression of Monocytes Subsets in Patients Diagnosed With Coronary Artery Atherosclerosis and Their Impact on Disease Severity.

Introduction Many studies have supported inflammation as a mediator of lipoprotein (a) (Lp(a)) induced increase in cardiovascular disease risk, as it has pro-inflammatory effects on endothelial cells and monocytes. Aim This study aims to correlate Lp(a) level with different monocyte subsets in coronary atherosclerotic patients with different severity. Method The study included 60 patients with a mean age of 53.

Examining patient safety protocols amidst the rise of digital health and telemedicine: nurses' perspectives.

Background: Integrating digital health and telemedicine technologies is transforming healthcare delivery. In light of this transition, it is critical to ascertain the efficacy of patient safety protocols and evaluate the awareness of healthcare professionals, particularly nurses, regarding the integration of digital health technologies.

Aim: This study examines the factors influencing the successful adoption of digital health and telemedicine technologies from the nurses' perspective, focusing on ensuring patient safety and enhancing organizational readiness for digital health integration.

Tailoring nursing interventions to empower patients: personal coping strategies and self-management in type 2 diabetes care.

Background: Diabetes is one of the most common chronic diseases that severely reduce a patient's quality of life. Effective self-care and management are critical for maintaining blood glucose levels and preventing complications.

Aim: This study evaluates the effectiveness of a structured diabetes self-management education program on patients' self-management behaviors, empowerment, and activation levels.

Carnitine supplementation in progressive supranuclear palsy.

Mitochondrial dysfunction has been implicated in the pathogenesis of several neurodegenerative disorders, including progressive supranuclear palsy (PSP). PSP is a Parkinsonian syndrome characterized by a rapidly progressive state that manifests itself as tremors, bradykinesia, and supranuclear gaze palsy. Carnitine plays an essential role in mitochondrial function by transporting fatty acids across the mitochondrial membrane to be used in energy production.

Impact of the COVID-19 Pandemic on Physical Therapy Clinical Practice in Egypt: A Cross-Sectional Study.

Background The coronavirus disease 2019 (COVID-19) was an expanding pandemic caused by a new strain of the coronavirus family known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). No previous studies have examined the impact of COVID-19 pandemic on physical therapy practice in Egypt. Objectives This study aimed to assess the impact of COVID-19 pandemic on physical therapy clinical practice in Egypt five months after the pandemic declaration.

Fast and effective assessment of 4-chlorophenol as a persistent organic pollutant (POP) using a multi-walled carbon nanotube-modified screen-printed carbon electrode (C/MWCNT-COOH/SPCE).

In this study, a rapid, precise, and targeted electroanalytical method was developed for the trace determination of 4-chlorophenol (4-CP). The study reports the use of cyclic voltammetry (CV) to characterize the electrochemical response of 4-CP and the optimization of differential pulse voltammetry (DPV) settings for its sensitive quantification. Screen-printed carbon electrodes (SPCEs) were selected for the sensitive detection of 4-CP using DPV.

Advancements in Brain Aneurysm Management: Integrating Neuroanatomy, Physiopathology, and Neurosurgical Techniques.

Brain aneurysms, characterized by abnormal bulging in blood vessels, pose significant risks if ruptured, necessitating precise neuroanatomical knowledge and advanced neurosurgical techniques for effective management. This article delves into the intricate neuroanatomy relevant to brain aneurysms, including the vascular structures and critical regions involved. It provides a comprehensive overview of the pathophysiology of aneurysm formation and progression.

A magnetic macroporous α-FeO/MnO nanocomposite as an efficient adsorbent for simple and rapid removal of Pb(II) from wastewater and electronic waste leachate.

A magnetic nanocomposite adsorbent, comprised of macroporous iron oxide/manganese oxide (α-FeO/MnO), is prepared, characterized, and used for lead(II) removal from both industrial wastewater and leachate of electronic waste. The synergistic interaction between iron oxide and manganese oxide significantly enhances the adsorption performance. The surface characteristics and structural composition of the nanocomposite are examined using high-resolution transmission microscopy, X-ray spectroscopy, and Brunauer-Emmett-Teller methods.

Stable self-assembled oral metformin-bridged nanocochleates against hepatocellular carcinoma.

Despite its established anti-diabetic activity, Metformin hydrochloride (MET) has been repurposed for the management of hepatocellular carcinoma (HCC). Owing to MET high aqueous solubility and poor oral permeability, a novel nanoplatform is sought to overcome the current challenges of traditional formulations. In this study, we developed MET-bridged nanocochleates (MET-CO) using a direct bridging method followed by optimization and assessment using various in-vitro and in-vivo pharmacokinetic methods.

Efficacy of 8-week daclatasvir-sofosbuvir regimen in chronic hepatitis C: a systematic review and meta-analysis.

Background: The high rates of the sustained virologic response 12 weeks after treatment (SVR12) in real world settings provoked the adoption of shortened courses of the costly direct-acting antivirals (DAAs) regimens. This study provides, to our knowledge, the first systematic review and meta-analysis for the efficacy of the shortened 8-week course of sofosbuvir (SOF) plus daclatasvir (DCV), the most accessible DAAs in the low-middle income countries (LMICs).

Methods: We performed a proportion meta-analysis to determine a reliable rate of SVR12 by pooling all studies that evaluated the results of the 8-week regimen of DCV + SOF.

Enhancing impact of dietary nano formulated quercetin on laying performance: egg quality, oxidative stability of stored eggs, intestinal immune and antioxidants related genes expression.

Background: Nutritional interventions with natural antioxidants can provide a pragmatic solution for modifying hens' performance and maintaining oxidative stability of eggs during storage. Quercetin is the most abundant flavonoids with potent antioxidant and immune stimulant activities. The concept of incorporating of quercetin, as potent antioxidant and immunostimulant, into effective nano-carriers (QNPs) has promoted their bioavailability and stability thus, their effectiveness for the first time were assessed on laying hens' performance and immunity, eggs quality during storage.

Open-set long-tailed recognition via orthogonal prototype learning and false rejection correction.

Learning from data with long-tailed and open-ended distributions is highly challenging. In this work, we propose OLPR, which is a new dual-stream Open-set Long-tailed recognition framework based on orthogonal Prototype learning and false Rejection correction. It consists of a Probabilistic Prediction Learning (PPL) branch and a Distance Metric Learning (DML) branch.

Microneedles integrated with atorvastatin-loaded pumpkisomes for breast cancer therapy: A localized delivery approach.

Breast cancer is the most common invasive cancer in women worldwide, having a significant impact on women's well-being. Early diagnosis of breast cancer followed by appropriate treatment is considered the best survival factor. Microneedles (MN) have been utilized for non-invasive localized breast cancer treatment.

Aminated reduced graphene oxide-CuFeO nanohybride adsorbent for efficient removal of imidacloprid pesticide.

To remove organic and inorganic agrochemicals from contaminated soil and water, adsorption has been regarded as a viable remediation approach. For the removal of organic pollutants, such as pesticides, cost-effective adsorbents have garnered a lot of interest. These include waste-derived materials, clay composites, metal-organic frameworks (MOFs), nanocomposites, and biochar-modified materials.