Publications by authors named "Kambiz Kamyab"
Background And Aims: Spitz nevus is a rare benign tumor classified among unusual melanocytic nevi. This study aimed to identify the demographic, clinical, and histopathological characteristics of Spitz nevus among Iranian patients.
Methods: This descriptive, retrospective study involved reviewing the records of patients diagnosed with Spitz nevus at a referral and academic hospital in Iran between 2016 and 2021.
Article Synopsis
- - Lichen planopilaris (LPP) is an inflammatory hair loss condition that often leads to irreversible scarring and can reactivate even after treatment, making early detection important for managing the disease.
- - This study assessed a new paper sign test, which involves combing hair over a white sheet to check for fallen hairs, comparing it to traditional methods based on clinical symptoms.
- - The results showed that the paper sign test allowed patients to detect reactivation of LPP sooner than those relying on clinical symptoms, indicating it is a reliable and practical method for early detection during remission.
Procalcitonin (PCT) is a peptide precursor of calcitonin, considered as an infection marker in many settings. Recently, a few studies reported its rise in some inflammatory processes such as still's disease, anaphylactic shock and Kawasaki disease. To investigate the serum level of PCT in patients with pemphigus vulgaris (PV) and examine the relationship between serum level of PCT and the severity of disease.
View Article and Find Full Text PDFBackground: Skin neoplasms, particularly basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), are prevalent forms of skin malignancies. To enhance accurate diagnosis, non-invasive techniques including high-frequency ultrasound (HFUS) are crucial. HFUS offers deeper penetration compared to reflectance confocal microscopy (RCM), and optical coherence tomography (OCT), making it valuable for examining skin structures.
View Article and Find Full Text PDFWorldwide, squamous cell carcinoma (SCC) incidence is rising. The literature debates the human papillomavirus (HPV)'s role in cutaneous SCC development. We examined HPV histopathology in SCC samples in this study.
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- Human protothecosis is a rare infection caused by the Prototheca species, and it primarily affects immunocompromised individuals.
- A case study of a 24-year-old man with skin lesions was reported, alongside a review of 54 disseminated protothecosis cases, showing a predominance in males and cases caused mainly by P. wickerhamii.
- Treatment options include Amphotericin B for severe infections, while localized cases may require surgical intervention; early diagnosis relies on recognizing distinct skin appearances.
Article Synopsis
- * The condition is characterized by itchy, blistering skin lesions, primarily affecting areas like the axilla and groin, due to IgA autoantibodies disrupting cell adhesion in the skin.
- * The study presents a case where a 50-year-old male with severe IgA pemphigus had a poor response to Dapsone but was successfully treated with an injection of the TNFa inhibitor, adalimumab.
The manuscript describes a case of a 68-year-old woman with a pruritic nodule and yellow cobblestone plaque on her abdomen. Biopsy results showed trans epidermal illumination of basophilic elastic fibres in the reticular dermis with calcium deposits. The diagnosis was perforating calcific elastosis, an acquired rare condition mostly seen in obese, multiparous, middle-aged women.
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- This study explores the potential link between herpes simplex virus (HSV) and pemphigus vulgaris by evaluating HSV presence in oral lesions of affected patients.
- The research involved comparing 52 pemphigus patients with 52 control patients and found HSV1 in a significantly higher percentage of the pemphigus group, although no notable connection with disease severity was established.
- The findings suggest that while HSV1 is prevalent in oral lesions of pemphigus vulgaris, its exact impact on the disease remains unclear, and acyclovir treatment could be beneficial for managing these patients.
Introduction: Few studies have evaluated the histopathological characteristics of clinical rosacea subtypes in detail.
Objectives: To assess rosacea histopathological features in correspondence to clinical subgroups.
Methods: The histopathological findings of 204 rosacea patients were analyzed retrospectively and were compared among clinical subtypes.
Introduction: The two less-known subtypes of lichen planus (LP) are lichen planus actinicus (LPA) and lichen planus pigmentosus (LPP), with the highest prevalence in the Middle East.
Objectives: We aimed to evaluate the clinicopathological profile of these patients.
Methods: Three hundred and seven cases including 184 LPA and 123 LPP patients were recruited from the registered pathology reports of Razi Skin Hospital of Tehran from April 2016 to March 2021.
Scleromyxedema is a rare but important mucinosis disorder of the skin that is presented with dermatological manifestations such as waxy papules, diffuse induration, and nondermatologic involvements like neurological and renal disorders. We report a case series of the data regarding the characteristics and treatment of 14 patients diagnosed with scleromyxedema and their follow-up. Patients entered the study based on scleromyxedema diagnosis criteria.
View Article and Find Full Text PDFAim: To examine the prevalence of this novel pattern among Iranian patients with pemphigus and peruse the relationship between the presence of a punctate pattern with clinical severity of disease and histopathological findings.
Methods: One hundred recently diagnosed patients with pemphigus were enrolled. DIF evaluation and routine light microscopy were performed on their biopsy specimens.
Plexiform schwannoma is an uncommon soft tissue tumor that could even rarely presented on the foot and toes.
View Article and Find Full Text PDFBackground: Angiofibromas are common benign skin lesions that are diagnosed clinically and histopathologically. Fibrous papule (FP) is one of the clinical types of angiofibromas located primarily on the nose.
Methods: The cases with the confirmed diagnosis of angiofibroma were enrolled.
Cutaneous lymphadenoma (CL) is a rare skin tumor supposedly derived from the pilosebaceous unit. Since its description in 1987, fewer than 60 cases have been documented. Herein we report a case of CL presenting as a small nodule on the forehead of a young female.
View Article and Find Full Text PDFEN is a hamartomatous proliferation of keratinocytes. The most common dermoscopic feature of EN is large brown circles in the absence of pigment network which is similar in different histopathological variants including epidermolytic hyperkeratotic.
View Article and Find Full Text PDFBackground: Skin cancer is the most common cancer worldwide and commonly classified into malignant melanoma (MM) and Nonmelanoma skin cancers (NMSCs), which mainly include basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The extent to which Long Interspersed Element-1 (LINE-1, L1) ORF1p is expressed in cutaneous malignancies remains to be evaluated. This study aimed to assess LINE-1 ORF1p immunoreactivity in various skin cancer subtypes.
View Article and Find Full Text PDFBackground: Benign cutaneous lesions, so-called cysts, are frequently seen in clinics and might evoke cosmetic and psychosocial concerns.
Aim: This study aimed to demonstrate the clinicopathologic findings of these lesions and also the importance of histological evaluation for prevention of misdiagnosing a benign-appearing malignant lesion.
Methods: A descriptive study was conducted of 2,438 cases who had a diagnosis of cyst confirmed with pathology.
Granuloma annulare after Botulonium toxin A injection: A rare association.
J Cosmet Dermatol
October 2020
Background: Botulinum toxin is generally considered safe and has been used in constantly expanded cosmetic and therapeutic indications. However, long-term side effects such as granulomatous reactions have been associated with this drug.
Aims: We aim to evaluate a rare reaction to Botulonium toxin A injection.