Real-Time MRI-Guided Stereotactic Aspiration of Spontaneous Intracerebral Hematoma: A Preclinical Feasibility Study.

Background: Minimally invasive surgical techniques have reinvigorated the role of surgical options for spontaneous intracranial hematomas; however, they are limited by the lack of real-time feedback on the extent of hematoma evacuation.

Objective: To describe the development of a MRI-guided catheter-based aspiration system, the ClearPoint Pursuit Neuroaspiration Device (ClearPoint Neuro) and validation in phantom models.

Methods: In this preclinical experimental trial, 8 phantom brains with skull models were created to simulate an intracranial hematoma with 2 clot sizes, 30 cc (small clot) and 60 cc (large clot).

Prospective Clinical Implementation of a Novel Magnetic Resonance Tracking Device for Real-Time Brachytherapy Catheter Positioning.

Purpose: We designed and built dedicated active magnetic resonance (MR)-tracked (MRTR) stylets. We explored the role of MRTR in a prospective clinical trial.

Methods And Materials: Eleven gynecologic cancer patients underwent MRTR to rapidly optimize interstitial catheter placement.

Measurement accuracy of different active tracking sequences for interventional MRI.

Purpose: To compare the spatial accuracy of three typical active tracking sequences using a new, unique phantom design.

Materials And Methods: Three different tracking sequences (Single Echo, Dual Echo and Hadamard Multiplexed) were compared with each other in a phantom study with respect to their positional accuracy. A custom-built phantom was constructed to conduct the experiments with precise framework conditions which facilitated sufficient measurement accuracy.

Real-time magnetic resonance imaging-guided radiofrequency atrial ablation and visualization of lesion formation at 3 Tesla.

Background: Magnetic resonance imaging (MRI) allows visualization of location and extent of radiofrequency (RF) ablation lesion, myocardial scar formation, and real-time (RT) assessment of lesion formation. In this study, we report a novel 3-Tesla RT -RI based porcine RF ablation model and visualization of lesion formation in the atrium during RF energy delivery.

Objective: The purpose of this study was to develop a 3-Tesla RT MRI-based catheter ablation and lesion visualization system.